DNA interaction and antioxidant studies of ruthenium(II) complexes containing mixed ligands

被引：1
|
作者：
Sampath, Krishnan [1 ]
Mohanraj, Maruthachalam [2 ]
Jayabalakrishnan, Chinnasamy [2 ]
机构：
[1] Kumaraguru Coll Technol, Dept Chem, Coimbatore, Tamil Nadu, India
[2] Sri Ramakrishna Mission Vidyalaya Coll Arts & Sci, Post Grad & Res Dept Chem, Coimbatore 641020, Tamil Nadu, India
来源：
INORGANIC AND NANO-METAL CHEMISTRY | 2017年 / 47卷 / 07期
关键词：
Ruthenium(II) complexes; benzothiazole; DNA binding; DNA cleavage; antioxidants; IN-VITRO; CYTOTOXIC ACTIVITIES; ANTIFUNGAL ACTIVITY; CRYSTAL-STRUCTURES; SCHIFF-BASES; BINDING; TRIPHENYLPHOSPHINE; CLEAVAGE; TERNARY; DESIGN;
D O I：
10.1080/24701556.2017.1284089
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
Ruthenium(II) complexes of mixed ligands (benzothiazolyl Schiff base, PPh3, and AsPh3) have been synthesized. Structural features of the ligands and complexes were determined by various physicochemical and spectral techniques. In order to ascertain the potential of the above-synthesized compounds towards biomolecular interactions, titration experiments involving interaction with calf thymus DNA (CT-DNA) were carried out. A gel electrophoresis pictogram demonstrated the ability of the complexes to cleave the CT-DNA. The ligands and complexes have shown significant antioxidant activity.
引用
收藏
页码：1049 / 1056
页数：8
相关论文
共 50 条
  • [31] Synthesis, characterization and interaction of mixed polypyridyl ruthenium(II) complexes with calf thymus DNA
    Liu, JG
    Zhang, QL
    Ji, LN
    Cao, YY
    Shi, XF
    TRANSITION METAL CHEMISTRY, 2001, 26 (06) : 733 - 738
  • [32] RUTHENIUM(II) ISOCYANIDE COMPLEXES CONTAINING TRICHLOROSTANNATE AND OTHER LIGANDS
    PRATER, BE
    INORGANIC & NUCLEAR CHEMISTRY LETTERS, 1971, 7 (11): : 1071 - &
  • [33] Novel polypyridyl ruthenium(II) complexes containing oxalamidines as ligands
    Ruben, M
    Rau, S
    Skirl, A
    Krause, K
    Görls, H
    Walther, D
    Vos, JG
    INORGANICA CHIMICA ACTA, 2000, 303 (02) : 206 - 214
  • [34] Luminescent α-diimine complexes of ruthenium(II) containing scorpionate ligands
    Huang, L
    Seward, KJ
    Sullivan, BP
    Jones, WE
    Mecholsky, JJ
    Dressick, WJ
    INORGANICA CHIMICA ACTA, 2000, 310 (02) : 227 - 236
  • [35] Studies on Photocleavage, DNA Binding, Cytotoxicity, and Docking Studies of Ruthenium(II) Mixed Ligand Complexes
    Kumar, Yata Praveen
    Devi, C. Shobha
    Srishailam, A.
    Deepika, N.
    Kumar, V. Ravi
    Reddy, P. Venkat
    Nagasuryaprasad, K.
    Singh, Surya S.
    Nagababu, Penumaka
    Satyanarayana, S.
    JOURNAL OF FLUORESCENCE, 2016, 26 (06) : 2119 - 2132
  • [36] Studies on Photocleavage, DNA Binding, Cytotoxicity, and Docking Studies of Ruthenium(II) Mixed Ligand Complexes
    Yata Praveen Kumar
    C. Shobha Devi
    A. Srishailam
    N. Deepika
    V. Ravi Kumar
    P. Venkat Reddy
    K Nagasuryaprasad
    Surya S. Singh
    Penumaka Nagababu
    S. Satyanarayana
    Journal of Fluorescence, 2016, 26 : 2119 - 2132
  • [37] Spectroelectrochemical studies on some new ruthenium(II) complexes containing both cyanide and isocyanide ligands
    al Dulaimi, JP
    Clark, RJH
    Saavedra, M
    Salam, MA
    INORGANICA CHIMICA ACTA, 2000, 300 (300-302) : 175 - 180
  • [38] Studies on ruthenium(III) complexes of amide group containing ligands
    Raju, K.
    Dayakar, G.
    ASIAN JOURNAL OF CHEMISTRY, 2008, 20 (06) : 4148 - 4152
  • [39] COPPER(II) COMPLEXES CONTAINING MIXED-LIGANDS
    CHAUDHURI, AH
    JOURNAL OF THE INDIAN CHEMICAL SOCIETY, 1995, 72 (10) : 713 - 714
  • [40] Polypyridine ruthenium(II) complexes containing mixed ligands. Synthesis, spectroscopic and photophysical and electrochemical properties
    Jing, BW
    Wang, WQ
    Zhang, MH
    Shen, T
    DYES AND PIGMENTS, 1998, 37 (02) : 177 - 186
12345