REBASE - enzymes and genes for DNA restriction and modification

被引:187
|
作者
Roberts, Richard J. [1 ]
Vincze, Tamas [1 ]
Posfai, Janos [1 ]
Macelis, Dana [1 ]
机构
[1] New England Biolabs Inc, Ipswich, MA 01938 USA
关键词
D O I
10.1093/nar/gkl891
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
REBASE is a comprehensive database of information about restriction enzymes, DNA methyltransferases and related proteins involved in the biological process of restriction-modification. It contains fully referenced information about recognition and cleavage sites, isoschizomers, neoschizomers, commercial availability, methylation sensitivity, crystal and sequence data. Experimentally characterized homing endonucleases are also included. All newly sequenced genomes are analyzed for the presence of putative restriction systems and these data are included within the REBASE. The contents or REBASE may be browsed from the web (http://rebase.neb.com/rebase/rebase.ftp.html>) and selected compilations can be downloaded by ftp (ftp.neb.com). Additionally, monthly updates can be requested via email.
引用
收藏
页码:D269 / D270
页数:2
相关论文
共 50 条
  • [41] Translocation-coupled DNA cleavage by the Type ISP restriction-modification enzymes
    Chand, Mahesh K.
    Nirwan, Neha
    Diffin, Fiona M.
    van Aelst, Kara
    Kulkarni, Manasi
    Pernstich, Christian
    Szczelkun, Mark D.
    Saikrishnan, Kayarat
    NATURE CHEMICAL BIOLOGY, 2015, 11 (11) : 870 - U93
  • [42] Translocation-coupled DNA cleavage by the Type ISP restriction-modification enzymes
    Mahesh K Chand
    Neha Nirwan
    Fiona M Diffin
    Kara van Aelst
    Manasi Kulkarni
    Christian Pernstich
    Mark D Szczelkun
    Kayarat Saikrishnan
    Nature Chemical Biology, 2015, 11 : 870 - 877
  • [43] Structural insights into DNA sequence recognition by Type ISP restriction-modification enzymes
    Kulkarni, Manasi
    Nirwan, Neha
    van Aelst, Kara
    Szczelkun, Mark D.
    Saikrishnan, Kayarat
    NUCLEIC ACIDS RESEARCH, 2016, 44 (09) : 4396 - 4408
  • [44] SITE-SPECIFIC INHIBITION OF ECORI RESTRICTION MODIFICATION ENZYMES BY A DNA TRIPLE HELIX
    HANVEY, JC
    SHIMIZU, M
    WELLS, RD
    NUCLEIC ACIDS RESEARCH, 1990, 18 (01) : 157 - 161
  • [45] A model for the evolution of prokaryotic DNA restriction-modification systems based upon the structural malleability of Type I restriction-modification enzymes
    Bower, Edward K. M.
    Cooper, Laurie P.
    Roberts, Gareth A.
    White, John H.
    Luyten, Yvette
    Morgan, Richard D.
    Dryden, David T. F.
    NUCLEIC ACIDS RESEARCH, 2018, 46 (17) : 9067 - 9080
  • [46] CLONING AND SEQUENCING OF GENES ENCODING THE TTHHB8I RESTRICTION AND MODIFICATION ENZYMES - COMPARISON WITH THE ISOSCHIZOMERIC TAQI ENZYMES
    BARANY, F
    DANZITZ, M
    ZEBALA, J
    MAYER, A
    GENE, 1992, 112 (01) : 3 - 12
  • [47] ISOLATION OF MODIFICATION RESTRICTION ENZYMES HPAI AND HPAII
    BOGDARINA, IG
    ZINKEVICH, VE
    BURYANOV, YI
    BAEV, AA
    BIOCHEMISTRY-MOSCOW, 1985, 50 (10) : 1415 - 1420
  • [48] TAXONOMIC SPECIFICITY OF RESTRICTION-MODIFICATION ENZYMES
    JANULAITIS, A
    KAZLAUSKIENE, R
    LAZAREVICIUTE, L
    GILVONAUSKAITE, R
    STEPONAVICIENE, D
    JAGELAVICIUS, M
    PETRUSYTE, M
    BITINAITE, J
    VEZEVICIUTE, Z
    KIUDULIENE, E
    BUTKUS, V
    GENE, 1988, 74 (01) : 229 - 232
  • [49] CHLORELLA VIRUSES CODE FOR RESTRICTION AND MODIFICATION ENZYMES
    VANETTEN, JL
    XIA, Y
    BURBANK, DE
    NARVA, KE
    GENE, 1988, 74 (01) : 113 - 115
  • [50] COMPLETE AMINO-ACID-SEQUENCES AND DNA-BINDING OF ECO RI DNA RESTRICTION AND MODIFICATION ENZYMES
    MODRICH, P
    NEWMAN, A
    RUBIN, RA
    JACK, W
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1980, 180 (AUG): : 158 - BIOL