'Long-COVID': a cross-sectional study of persisting symptoms, biomarker and imaging abnormalities following hospitalisation for COVID-19

被引：569

作者：

Mandal, Swapna ^{[1
]}

Barnett, Joseph ^{[2
]}

Brill, Simon E. ^{[1
]}

Brown, Jeremy S. ^{[3
,4
]}

Denneny, Emma K. ^{[4
]}

Hare, Samanjit S. ^{[2
]}

Heightman, Melissa ^{[4
]}

Hillman, Toby E. ^{[4
]}

Jacob, Joseph ^{[5
,6
]}

Jarvis, Hannah C. ^{[1
]}

Lipman, Marc C., I ^{[1
,3
]}

Naidu, Sindhu B. ^{[1
]}

Nair, Arjun ^{[6
]}

Porter, Joanna C. ^{[3
,4
]}

Tomlinson, Gillian S. ^{[4
,7
]}

Hurst, John R. ^{[1
,3
]}

机构：

[1] Royal Free London NHS Fdn Trust, Resp Med, London, England

[2] Royal Free London NHS Fdn Trust, Dept Radio, London, England

[3] UCL, UCL Resp, London NW3 2PF, England

[4] Univ Coll London Hosp NHS Fdn Trust, Resp Med, London, England

[5] UCL, Ctr Med Image Comp, London, England

[6] Univ Coll London Hosp NHS Fdn Trust, Dept Radiol, London, England

[7] UCL, Infect & Immun, London, England

来源：

THORAX | 2021年 / 76卷 / 04期

基金：

英国惠康基金;

关键词：

viral infection; respiratory infection;

D O I：

10.1136/thoraxjnl-2020-215818

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Large numbers of people are being discharged from hospital following COVID-19 without assessment of recovery. In 384 patients (mean age 59.9 years; 62% male) followed a median 54 days post discharge, 53% reported persistent breathlessness, 34% cough and 69% fatigue. 14.6% had depression. In those discharged with elevated biomarkers, 30.1% and 9.5% had persistently elevated d-dimer and C reactive protein, respectively. 38% of chest radiographs remained abnormal with 9% deteriorating. Systematic follow-up after hospitalisation with COVID-19 identifies the trajectory of physical and psychological symptom burden, recovery of blood biomarkers and imaging which could be used to inform the need for rehabilitation and/or further investigation.

引用

页码：396 / 398

页数：3

共 50 条

[21] Long-COVID syndrome and interstitial lung disease following COVID-19
Fesu, Dorottya
Polivka, Lorinc
Barczi, Eniko
Foldesi, Marcell
Horvath, Gabor
Bohacs, Aniko
Muller, Veronika
EUROPEAN RESPIRATORY JOURNAL, 2023, 62
[22] Illness perceptions in long-COVID: A cross-sectional analysis in adults
Bierbauer, W.
Luscher, J.
Scholz, U.
COGENT PSYCHOLOGY, 2022, 9 (01):
[23] Cross-Sectional Abdominal Imaging Findings in Patients With COVID-19
Shiralkar, Kaustubh
Chinapuvvula, Naga
Ocazionez, Daniel
CUREUS JOURNAL OF MEDICAL SCIENCE, 2020, 12 (08)
[24] Seroprevalence of COVID-19 in Oran: Cross-Sectional Study
Dali-Ali, Abdessamad
Derkaoui, Dalia Kheira
Zina, Mohamed
Oukebdane, Asmaa
MICROBIOLOGY SPECTRUM, 2023, 11 (04)
[25] COVID-19 in otolaryngologists: a cross-sectional multicenter study
Scapini, Fabricio
Lubianca Neto, Jose Faibes
Angeli, Roberto Dihl
Pozzer Krumenauer, Rita Carolina
Santanna, Ingrid Wendland
Oppermann, Luciana Pimentel
Atolini Junior, Nedio
Meotti, Camila Degen
Lacerda Elias, Caroline Catherine
de Britto Medeiros, Lilcia Helena
Roithmann, Renato
Castagno, Clarissa Delpizzo
de Carli, Adriana
Granzotto, Eduardo Homrich
Steffen, Nedio
Maahs, Gerson Schulz
BRAZILIAN JOURNAL OF OTORHINOLARYNGOLOGY, 2022, 88 (05) : S4 - S11
[26] COVID-19 seroprevalence in Pakistan: a cross-sectional study
Ahmad, Ahsan M.
Shahzad, Khurram
Masood, Mariumn
Umar, Maida
Abbasi, Fahad
Hafeez, Assad
BMJ OPEN, 2022, 12 (04):
[27] Household Transmission of COVID-19: A Cross-Sectional Study
Dutta, Siddhartha
Kaur, Rimple Jeet
Bhardwaj, Pankaj
Charan, Jaykaran
Bist, Sunil Kumar Singh
Detha, Mohan Dan
Kanchan, Tanuj
Sharma, Praveen
Misra, Sanjeev
INFECTION AND DRUG RESISTANCE, 2020, 13 : 4637 - 4642
[28] Telogen effluvium and COVID-19: a cross-sectional study
Aldahish, A.
Vasudevan, R.
Salem, H.
Alqahtani, A.
Alqasim, S.
Alqhatani, A.
Al Shahrani, M.
Al Mohsen, L.
Hajla, M.
Calina, D.
Sharifi-Rad, J.
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, 2023, 27 (16) : 7823 - 7830
[29] Persisting Symptoms After COVID-19
Foerster, Christian
Colombo, Miriam Giovanna
Wetzel, Anna-Jasmin
Martus, Peter
Joos, Stefanie
DEUTSCHES ARZTEBLATT INTERNATIONAL, 2022, 119 (10): : 167 - +
[30] Mental health difficulties in students with suspected COVID-19 symptoms and students without suspected COVID-19 symptoms: A cross-sectional comparative study during the COVID-19 pandemic
Sultana, Mst Sadia
Khan, Abid Hasan
Hossain, Sahadat
Hasan, M. Tasdik
CHILDREN AND YOUTH SERVICES REVIEW, 2021, 128

← 1 2 3 4 5 →