Kidney injury associated with monoclonal gammopathies: Perspectives on diagnosis and treatment

被引：0
|
作者：
Kozlovskaya, L. V. [1 ]
Rameev, V. V. [1 ]
Mrykhin, N. N. [1 ]
Kogarko, I. N. [2 ]
Kogarko, B. S. [2 ]
机构：
[1] IM Sechenov First Moscow Med Univ, Minist Hlth Russia, Moscow, Russia
[2] Russian Acad Sci, NN Semenov Inst Chem Phys, Moscow, Russia
来源：
TERAPEVTICHESKII ARKHIV | 2015年 / 87卷 / 06期
关键词：
monoclonal gammopathies; amyloidosis; kidney diseases; PRIMARY SYSTEMIC AMYLOIDOSIS; UNDETERMINED SIGNIFICANCE; LIGHT;
D O I：
10.17116/terarkh2015876108-111
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
It is currently well justified that monoclonal gammopathies are the most important predictor for kidney diseases, including glomerulonephritis. To determine a correlation of nephropathy with oligosecretory gammopathy is of fundamental importance, as the treatment of these patients necessitates the use of special chemotherapy regimens to eliminate a pathological clone of lymphocytes or plasmocytes. If this clone is not eliminated, injury of the organ may recur to develop its failure. The principles of this therapy have been presently tried out by the example of AL-amyloidosis and showed its efficiency and relatively low toxicity.
引用
收藏
页码：108 / 111
页数：4
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