Serum HGF levels in acute renal rejection after living related renal transplantation

被引：19

作者：

Takada, S ^{[1
]}

Namiki, M ^{[1
]}

Takahara, S ^{[1
]}

Matsumiya, K ^{[1
]}

Kondoh, N ^{[1
]}

Kokado, Y ^{[1
]}

Matsumoto, K ^{[1
]}

Nakamura, T ^{[1
]}

Okuyama, A ^{[1
]}

机构：

[1] OSAKA UNIV,SCH MED,DEPT UROL,SUITA,OSAKA 565,JAPAN

来源：

TRANSPLANT INTERNATIONAL | 1996年 / 9卷 / 02期

关键词：

kidney transplantation; hepatocyte growth factor; rejection;

D O I：

10.1007/BF00336393

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Hepatocyte growth factor (HGF), a long sought-after hepatotrophic factor, has recently been shown to act as a renotrophic factor in regeneration of the kidney. We investigated serum HGF levels in 16 renal transplant patients. In patients with acute rejection, the serum HGF level was markedly increased (over 1 ng/ml), and its elevation was accompanied by an increase in serum creatinine and blood urea nitrogen (BUN). In contrast, serum HGF levels were continuously low in patients without rejection. We conclude that serum HGF may become a clinically useful marker for the assessment of acute renal rejection.

引用

页码：151 / 154

页数：4

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