Unilateral testicular torsion: Protective effect of verapamil on contralateral testicular histology

被引:20
|
作者
Sarica, K [1 ]
Bakir, K [1 ]
Yagci, F [1 ]
Erbagci, A [1 ]
Topcu, O [1 ]
Uysal, O [1 ]
机构
[1] Univ Gaziantep, Sahinbey Hosp, Dept Urol, Sch Med, TR-27070 Kolejtepe Gaziantep, Turkey
关键词
testicular torsion; tubular diameter; verapamil; histology;
D O I
10.1159/000030382
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
In this experimental study, it was our aim to reduce the effects of ischemic insults to the contralateral testicle after unilateral testicular torsion. The protective effect of a calcium channel blocking agent (verapamil) on the histology and the tubular diameter of contralateral testicle was evaluated, Following a definite period of unilateral testicular torsion (i.e., 4 h), the protective effect of this specific medication was evaluated both after detorsion and orchiectomy procedures, The results of our study demonstrated the protective effect of verapamil on both parameters, especially in animals undergoing orchiectomy. The majority of the specimens demonstrated normal histologic findings together with preserved tubular structures after a 1-week period under verapamil medication.
引用
收藏
页码:159 / 163
页数:5
相关论文
共 50 条
  • [21] Effect of Unilateral Iatrogenic Testicular Torsion on the Contralateral Testis in Rats: Prepubertal and Postpubertal
    Ahmadnia, Hassan
    Dolati, Mahmoud
    Ghanadi, Alireza
    YounesiRostami, Mehdi
    Rezayat, AlirezaAkhavan
    UROLOGY JOURNAL, 2019, 16 (05) : 501 - 505
  • [22] ULTRASTRUCTURAL STUDIES OF THE CONTORTED AND CONTRALATERAL TESTICLE IN UNILATERAL TESTICULAR TORSION
    HORICA, CA
    HADZISELIMOVIC, F
    KREUTZ, G
    BANDHAUER, K
    EUROPEAN UROLOGY, 1982, 8 (06) : 358 - 362
  • [23] Unilateral testicular seminoma with simultaneous contralateral torsion: a case report
    Kazumi Taguchil
    Takahiro Yasui
    Taku Naiki
    Yukihiro Umemoto
    Yoshiyuki Kojima
    Noriyasu Kawai
    Keiichi Tozawa
    Yutaro Hayashi
    Kenjiro Kohri
    Journal of Medical Case Reports, 6 (1)
  • [24] Increased apoptosis in the contralateral testis in patients with unilateral testicular torsion
    Hadziselimovic, F
    Herzog, B
    Geneto, R
    Emmons, LR
    PEDIATRICS, 1997, 100 (03) : 574 - 574
  • [25] HORMONE PROFILES AND CONTRALATERAL TESTICULAR HISTOLOGY IN DOWNS-SYNDROME WITH UNILATERAL TESTICULAR-TUMOR
    SASAGAWA, I
    NAKADA, T
    HASHIMOTO, T
    ISHIGOOKA, M
    IZUMIYA, K
    KUBOTA, Y
    TOMARU, M
    ARCHIVES OF ANDROLOGY, 1993, 30 (02): : 93 - 98
  • [26] Evaluation of contralateral testicular damage after unilateral testicular torsion by serum inhibin B levels
    Özkan, KU
    Küçükaydin, M
    Muhtaroglu, S
    Kontas, O
    JOURNAL OF PEDIATRIC SURGERY, 2001, 36 (07) : 1050 - 1053
  • [27] Effect of curcumin on ipsilateral and contralateral testes after unilateral testicular torsion in a rat model
    Basaran, Umit Nusret
    Dokmeci, Dikmen
    Yalcin, Omer
    Inan, Mustafa
    Kanter, Mehmet
    Aydogdu, Nurettin
    Turan, Nesrin
    UROLOGIA INTERNATIONALIS, 2008, 80 (02) : 201 - 207
  • [28] The effect of vitamin E on ipsilateral and contralateral testis following unilateral testicular torsion in rats
    Turan, C
    Kucukaydin, N
    Bekerecioglu, A
    Kazez, A
    Dogan, P
    Kucukaydin, M
    RESEARCH IN EXPERIMENTAL MEDICINE, 1996, 196 (04) : 243 - 246
  • [29] UNILATERAL TESTICULAR TORSION - ABNORMAL HISTOLOGICAL-FINDINGS IN THE CONTRALATERAL TESTIS - CAUSE OR EFFECT
    LAOR, E
    FISCH, H
    TENNENBAUM, S
    SESTERHENN, I
    MOSTOFI, K
    REID, RE
    BRITISH JOURNAL OF UROLOGY, 1990, 65 (05): : 520 - 523
  • [30] Effects of Chemical Sympathectomy on Contralateral Testicular Histology and Fertility in Unilateral Vasectomy
    Kutlu, Omer
    Kocabiyik, Ali
    Koksal, Ismail Turker
    Guntekin, Erol
    JOURNAL OF KOREAN MEDICAL SCIENCE, 2009, 24 (05) : 849 - 852