Synthesis of a 14 beta-hydroxysteroid using the transannular Diels-Alder strategy

被引：0
|
作者：
Ouellet, L [1 ]
Langlois, P [1 ]
Deslongchamps, P [1 ]
机构：
[1] UNIV SHERBROOKE,FAC SCI,DEPT CHIM,ORGAN SYNTH LAB,SHERBROOKE,PQ J1K 2R1,CANADA
来源：
SYNLETT | 1997年 / 06期
关键词：
cardenolides; cardiac glycosides; 14; beta-hydroxysteroid; transannular Diels-Alder reaction; macrocyclisation;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Macrocyclic TCC triene 1, generated by an intramolecular alkylation of a beta-ketoester on a pi-allylpalladium complex followed by dehydrogenation, underwent a highly stereoselective transannular Diels-Alder reaction affording the tetracyclic compound 2 in an excellent yield.
引用
收藏
页码：689 / 690
页数：2
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