Glaucogenin E, a new C21 steroid from Cynanchum stauntonii

被引:11
|
作者
Zhang, Mi [1 ]
Wang, Jun-Song [1 ]
Luo, Jun [1 ]
Wei, Dan-Dan [1 ]
Kong, Ling-Yi [1 ]
机构
[1] China Pharmaceut Univ, Dept Nat Med Chem, Nanjing 210009, Peoples R China
基金
中国国家自然科学基金;
关键词
glaucogenin E; steroid sapogenin; Cynanchum stauntonii; cytotoxicity; GLYCOSIDES; ROOT;
D O I
10.1080/14786419.2012.665914
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Glaucogenin E (1), a new C-21 steroid sapogenin, along with three known ones (24) were isolated from the rhizomes of Cynanchum stauntonii (Decne.) Schltr. ex Levl. Their structures were established mainly by the spectroscopic analysis, including 2D NMR. All the isolated compounds were evaluated for their cytotoxicity against human cancer cell lines HeLa, Bel-7402, SGC-7901 and BGC-823.
引用
收藏
页码:176 / 180
页数:5
相关论文
共 50 条
  • [41] Structure determination of two new C21 steroidal glycosides from Cynanchum komarovii
    Zhao, Dan
    Tang, Ming-Xu
    Su, Shan-Shan
    Lu, Xiao-Jie
    Wang, Yu-Bo
    Chen, Shao-Fei
    Wang, Hai-Feng
    Chen, Gang
    Pei, Yue-Hu
    JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2018, 20 (09) : 852 - 859
  • [42] C21 Steroidal Glycosides from Acidic Hydrolysate of Cynanchum otophyllum
    Yi-bin Zhao
    Quan-shui Fan
    Gui-li Xu
    Zi-liang Feng
    Xiao-jiang Hao
    Chinese Herbal Medicines, 2014, (04) : 319 - 323
  • [43] C21 steroidal glycosides with cytotoxic activities from Cynanchum otophyllum
    Dong, Jinrun
    Peng, Xingrong
    Li, Lei
    Lu, Shuangyang
    Zhou, Lin
    Qiu, Minghua
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 28 (09) : 1520 - 1524
  • [44] C21 steroidal glycosides with cytotoxic activity from Cynanchum taihangense
    Wang, Yu-Bo
    Su, Shan-Shan
    Chen, Shao-Fei
    Tang, Ming-Xu
    Chen, Gang
    Zhao, Dan
    Sang, Xia-Nan
    Si, Ying-Ying
    Wang, Hai-Feng
    Pei, Yue-Hu
    PHYTOCHEMISTRY LETTERS, 2017, 20 : 218 - 223
  • [45] Immunosuppressive C21 steroidal glycosides from the root of Cynanchum atratum
    Zhang, Zhi-Jun
    Ding, Mei-Ling
    Tao, Li-Jun
    Zhang, Mian
    Xu, Xiang-Hong
    Zhang, Chao-Feng
    FITOTERAPIA, 2015, 105 : 194 - 201
  • [46] Five new C21 steroidal glycosides from Cynanchum komarovii Al.!Iljinski
    Wang, LQ
    Shen, YM
    Xu, X
    Wei, YQ
    Zhou, J
    STEROIDS, 2004, 69 (05) : 319 - 324
  • [47] Two New C21 Steroidal Glycosides from the Stems of Cynanchum paniculatum KiTAG.
    Huang, Xin
    Tan, Ai-Min
    Yang, Shi-Bao
    Zhang, An-Yuan
    Zhang, Hua
    HELVETICA CHIMICA ACTA, 2009, 92 (05) : 937 - 943
  • [48] New C21 steroidal glycosides, cynotophyllosides M-O, from Cynanchum otophyllum
    Ma, Lie-Feng
    Miao, Cun-Tan
    Qian, Hao-Ying
    Wang, Peng-Fei
    Wang, Fa-Song
    Zhan, Zha-Jun
    Shan, Wei-Guang
    JOURNAL OF CHEMICAL RESEARCH, 2017, (04) : 195 - 198
  • [49] Three New Steroidal Glycosides from the Roots of Cynanchum stauntonii
    Yu, Jin-Qian
    Zhang, Zhi-Hui
    Deng, An-Jun
    Qin, Hai-Lin
    BIOMED RESEARCH INTERNATIONAL, 2013, 2013
  • [50] Five new steroidal glycosides from the roots of Cynanchum stauntonii
    Wang, Kaiming
    Li, Ang
    Zhang, Ruiling
    Li, Siying
    Zhang, Fang
    Zhao, Lei
    Zhao, Zhongxi
    Li, Shanzhong
    Cai, Jianhua
    Cao, Jimin
    PHYTOCHEMISTRY LETTERS, 2016, 16 : 178 - 184