The roles of arginines in the mechanism of 4-oxalocrotonate tautomerase (4-OT).

被引：0
|
作者：
Harris, TK
Legler, PM
Czerwinski, RM
Abeygunawardana, C
Massiah, MA
Stivers, JT
Whitman, CP
Mildvan, AS
机构：
[1] Jpohn Hopkins Med Sch, Baltimore, MD 21205 USA
[2] Univ Texas, Austin, TX 78712 USA
来源：
BIOPHYSICAL JOURNAL | 1999年 / 76卷 / 01期
关键词：
D O I：
暂无
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
引用
收藏
页码：A178 / A178
页数：1
相关论文
共 50 条
  • [41] An Unexpected Promiscuous Activity of 4-Oxalocrotonate Tautomerase: The cis-trans Isomerisation of Nitrostyrene
    Zandvoort, Ellen
    Geertsema, Edzard M.
    Baas, Bert-Jan
    Quax, Wim J.
    Poelarends, Gerrit J.
    CHEMBIOCHEM, 2012, 13 (13) : 1869 - 1873
  • [42] 4-Oxalocrotonate tautomerase: pH dependence of catalysis and pK(a) values of active site residues
    Stivers, JT
    Abeygunawardana, C
    Mildvan, AS
    Hajipour, G
    Whitman, CP
    BIOCHEMISTRY, 1996, 35 (03) : 814 - 823
  • [43] 4-OXALOCROTONATE TAUTOMERASE, AN ENZYME COMPOSED OF 62 AMINO-ACID-RESIDUES PER MONOMER
    CHEN, LH
    KENYON, GL
    CURTIN, F
    HARAYAMA, S
    BEMBENEK, ME
    HAJIPOUR, G
    WHITMAN, CP
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1992, 267 (25) : 17716 - 17721
  • [44] Kinetic and structural effects of mutations of the catalytic amino-terminal proline in 4-oxalocrotonate tautomerase
    Czerwinski, RM
    Johnson, WH
    Whitman, CP
    Harris, TK
    Abeygunawardana, C
    Mildvan, AS
    BIOCHEMISTRY, 1997, 36 (47) : 14551 - 14560
  • [45] Comparative analysis of two different amide-to-ester bond mutations in the β-sheet of 4-oxalocrotonate tautomerase
    Silinski, P
    Fitzgerald, MC
    BIOCHEMISTRY, 2003, 42 (21) : 6620 - 6630
  • [46] Critical Role of Substrate Conformational Change in the Proton Transfer Process Catalyzed by 4-Oxalocrotonate Tautomerase
    Javier Ruiz-Pernia, J.
    Garcia-Viloca, Mireia
    Bhattacharyya, Sudeep
    Gao, Jiali
    Truhlar, Donald G.
    Tunon, Inaki
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2009, 131 (07) : 2687 - 2698
  • [47] Evolution of enzymatic activity in the tautomerase superfamily: Mechanistic and structural consequences of the L8R mutation in 4-oxalocrotonate Tautomerase
    Poelarends, Gerrit J.
    Almrud, Jeffrey J.
    Serrano, Hector
    Darty, Joseph E.
    Johnson, William H., Jr.
    Hackert, Marvin L.
    Whitman, Christian P.
    BIOCHEMISTRY, 2006, 45 (25) : 7700 - 7708
  • [48] PRELIMINARY-ANALYSIS OF CRYSTALS OF 4-OXALOCROTONATE TAUTOMERASE, AN ENZYME COMPOSED OF UNUSUALLY SMALL MONOMERS
    DAVENPORT, RC
    WHITMAN, CP
    JOURNAL OF MOLECULAR BIOLOGY, 1993, 231 (02) : 509 - 512
  • [49] Kinetic, stereochemical, and structural effects of mutations of the active site arginine residues in 4-oxalocrotonate tautomerase
    Harris, TK
    Czerwinski, RM
    Johnson, WH
    Legler, PM
    Abeygunawardana, C
    Massiah, MA
    Stivers, JT
    Whitman, CP
    Mildvan, AS
    BIOCHEMISTRY, 1999, 38 (38) : 12343 - 12357
  • [50] The product of the natural reaction catalyzed by 4-oxalocrotonate tautomerase becomes an affinity label of its mutant
    Brik, A
    Dawson, PE
    Keinan, E
    BIOORGANIC & MEDICINAL CHEMISTRY, 2002, 10 (12) : 3891 - 3897
12345