Optimization of Systemic and Mucosal Immune Responses to SIV and HIV-1 Antigens Using Different Protocols of DNA and Protein Immunization in Macaques

被引:0
|
作者
Pavlakis, G. N. [1 ]
Jalah, R. [1 ]
Li, J. [1 ]
Valentin, A. [1 ]
Rosati, M. [1 ]
Patel, V. [1 ]
Kulkarni, V. [1 ]
Alicea, C. [1 ]
Beach, R. Kelly [1 ]
Guan, Y. [2 ]
Lifson, J. D. [3 ]
Hirsch, V. M. [4 ]
Venzon, D. [1 ]
Broderick, K. E. [5 ]
Sardesai, N. Y. [5 ]
Fouts, T. R. [6 ]
Pinter, A. [7 ]
LaBranche, C. [8 ]
Montefiori, D. C. [8 ]
Shen, S. [8 ]
Tomaras, G. D. [8 ]
Felber, B. K. [1 ]
机构
[1] NCI, Frederick, MD 21701 USA
[2] Inst Human Virol, Baltimore, MD USA
[3] SAIC Frederick Inc, Frederick, MD USA
[4] NIAID, Bethesda, MD 20892 USA
[5] Inovio Pharmaceut Inc, Blue Bell, PA USA
[6] Profectus BioSci Inc, Baltimore, MD USA
[7] Univ Med & Dent New Jersey, Newark, NJ 07103 USA
[8] Duke Univ, Med Ctr, Durham, NC USA
关键词
D O I
暂无
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
引用
收藏
页码:A19 / A19
页数:1
相关论文
共 50 条
  • [41] Immunization with an SIV-based IDLV Expressing HIV-1 Env 1086 Clade C Elicits Durable Humoral and Cellular Responses in Rhesus Macaques
    Negri, Donatella
    Blasi, Maria
    LaBranche, Celia
    Parks, Robert
    Balachandran, Harikrishnan
    Lifton, Michelle
    Shen, Xiaoying
    Denny, Thomas
    Ferrari, Guido
    Vescio, Maria Fenicia
    Andersen, Hanne
    Montefiori, David C.
    Tomaras, Georgia D.
    Liao, Hua-Xin
    Santra, Sampa
    Haynes, Barton F.
    Klotman, Mary E.
    Cara, Andrea
    MOLECULAR THERAPY, 2016, 24 (11) : 2021 - 2032
  • [42] Live attenuated rubella vectors expressing SIV and HIV vaccine antigens replicate and elicit durable immune responses in rhesus macaques
    Virnik, Konstantin
    Hockenbury, Max
    Ni, Yisheng
    Beren, Joel
    Pavlakis, George N.
    Felber, Barbara K.
    Berkower, Ira
    RETROVIROLOGY, 2013, 10
  • [43] Live attenuated rubella vectors expressing SIV and HIV vaccine antigens replicate and elicit durable immune responses in rhesus macaques
    Konstantin Virnik
    Max Hockenbury
    Yisheng Ni
    Joel Beren
    George N Pavlakis
    Barbara K Felber
    Ira Berkower
    Retrovirology, 10
  • [44] Activation of HIV-1-specific immune responses to an HIV-1 vaccine constructed from a replication-defective adenovirus vector using various combinations of immunization protocols
    Yoshida, T
    Okuda, K
    Xin, KQ
    Tadokoro, K
    Fukushima, J
    Toda, S
    Hagiwara, E
    Hamajima, K
    Koshino, T
    Saito, T
    CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 2001, 124 (03): : 445 - 452
  • [45] Cellular HIV-1 immune responses in natural infection and after genetic immunization
    Calarota, SA
    Wahren, B
    SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES, 2001, 33 (02) : 83 - 96
  • [46] Intramuscular Delivery of Plasmid-Encoded CCL27 Elicits Mucosal, but Not Systemic Immune Responses Against SIV in Rhesus Macaques
    Kraynyak, Kimberly A.
    Kutzler, Michele A.
    Cisper, Neil J.
    Yan, Jian
    Khan, Amir S.
    Draghia-Akli, Ruxandra
    Lewis, Mark G.
    Weiner, David B.
    MOLECULAR THERAPY, 2009, 17 : S16 - S16
  • [47] Combination of mucosal and systemic immunization routes elicit high level of HIV protective mucosal immune responses to CCR5
    Lopalco, L.
    Merati, V.
    Asti, V.
    Diomede, L.
    Clemente, F.
    AIDS RESEARCH AND HUMAN RETROVIRUSES, 2010, 26 (10) : A85 - A85
  • [48] Enhancement of mucosal immune responses to the influenza virus HA protein by alternative approaches to DNA immunization
    Sha, ZY
    Vincent, MJ
    Copans, RW
    IMMUNOBIOLOGY, 1999, 200 (01) : 21 - 30
  • [49] DNA and Protein Co-immunization Improves the Magnitude, Longevity, and mucosal dissemination of Immune Responses
    Pavlakis, George
    Valentin, Antonio
    Li, Jinyao
    Jalah, Rashmi
    Patel, Vainav
    Rosati, Margherita
    Kulkarni, Viraj
    Alicea, Candido
    Vargas-Inchaustegui, Diego
    Guan, Yongjun
    Venzon, David
    Sardesai, Niranjan
    Fouts, Timothy
    Pinter, Abraham
    Robert-Guroff, Marjorie
    Montefiori, David
    Shen, Shaunna
    Tomaras, Georgia
    Felber, Barbara
    JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 2014, 67 : 42 - 42
  • [50] DNA and Protein Co-immunization Improves the Magnitude, Longevity, and Mucosal Dissemination of Immune Responses
    Pavlakis, George N.
    Li, Jinyao
    Valentin, Antonio
    Jalah, Rashmi
    Patel, Vainav
    Rosati, Margherita
    Kulkarni, Viraj
    Alicea, Candido
    Vargas-Inchaustegui, Diego A.
    Guan, Yongjun
    Venzon, David
    Sardesai, Niranjan
    Fouts, Timothy R.
    Pinter, Abraham
    Robert-Guroff, Marjorie
    Montefiori, David C.
    Shen, Xiaoying
    Tomaras, Georgia D.
    Felber, Barbara K.
    AIDS RESEARCH AND HUMAN RETROVIRUSES, 2014, 30 : A63 - A64