Impact of UGT1A4, UGT2B7, and UGT2B15 pharmacogenetics on tamoxifen (TAM) metabolism.

被引：0
|
作者：
Lim, Joanne Siok-Liu
Ganchev, Boian
Singh, Onkar
Muerdter, Thomas E.
Yap, Yoon Sim
Ng, Raymond C. H.
Wong, Nan Soon
Schwab, Matthias
Chowbay, Balram
机构：
[1] Natl Canc Ctr, Div Med Sci, Lab Clin Pharmacol, Singapore, Singapore
[2] Dr Margarete Fischer Bosch Inst Clin Pharmacol, Stuttgart, Germany
[3] Univ Tubingen, Stuttgart, Germany
[4] Natl Canc Ctr, Div Med Sci, Singapore, Singapore
[5] Natl Canc Ctr Singapore, Singapore, Singapore
[6] Natl Canc Ctr, Singapore, Singapore
来源：
JOURNAL OF CLINICAL ONCOLOGY | 2013年 / 31卷 / 15期
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
2588
引用
收藏
页数：1
相关论文
共 50 条
  • [21] PHASE 2 METABOLISM OF LETROZOLE IS MEDIATED BY UGT2B7
    Precht, J. C.
    Schroth, W.
    Ganchev, B.
    Heinkele, G.
    Zanger, U. M.
    Brauch, H.
    Schwab, M.
    Muerdter, T. E.
    BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2013, 75 : 12 - 12
  • [22] Clopidogrel Carboxylic Acid Glucuronidation is Mediated Mainly by UGT2B7, UGT2B4, and UGT2B17: Implications for Pharmacogenetics and Drug-Drug Interactions
    Kahma, Helina
    Filppula, Anne M.
    Neuvonen, Mikko
    Tarkiainen, E. Katriina
    Tornio, Aleksi
    Holmberg, Mikko T.
    Itkonen, Matti K.
    Finel, Moshe
    Neuvonen, Pertti J.
    Niemi, Mikko
    Backman, Janne T.
    DRUG METABOLISM AND DISPOSITION, 2018, 46 (02) : 141 - 150
  • [23] The Human UGT2B7 Nanodisc
    Cook, Ian
    Asenjo, Anna B.
    Sosa, Hernando
    Leyh, Thomas S.
    DRUG METABOLISM AND DISPOSITION, 2020, 48 (03) : 198 - 204
  • [24] Physiologically Based Pharmacokinetic Modeling to Predict the Impact of Liver Cirrhosis on Glucuronidation via UGT1A4 and UGT2B7/2B4-A Case Study with MidazolamS
    Ozbey, Agustos C.
    Keemink, Janneke
    Wagner, Bjoern
    Pugliano, Alessandra
    Kraurohenbueurohl, Stephan
    Annaert, Pieter
    Fowler, Stephen
    Parrott, Neil
    Umehara, Kenichi
    DRUG METABOLISM AND DISPOSITION, 2024, 52 (07) : 614 - 625
  • [25] Influence of valproic acid concentration and polymorphism of UGT1A4*3, UGT2B7-161C > T and UGT2B7*2 on serum concentration of lamotrigine in Chinese epileptic children
    Liu, Limin
    Zhao, Limei
    Wang, Qiuning
    Qiu, Feng
    Wu, Xiujun
    Ma, Yanan
    EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2015, 71 (11) : 1341 - 1347
  • [26] Pharmacogenetics and the Role of UGT2B7 in the Disposition and Triglyceride Response to Fenofibrate
    Straka, Robert J.
    Li, Na
    Tsai, Alexander K.
    Arafah, Azher
    Ordovas, Jose M.
    Guillemette, Chantal
    Arnett, Donna K.
    CIRCULATION, 2008, 118 (18) : S326 - S326
  • [27] Genetic variations in UGT1A1 and UGT2B7 and endometrial cancer risk
    McGrath, Monica
    Lepine, Johanie
    Lee, I-Min
    Villeneuve, Lyne
    Buring, Julie
    Guillemette, Chantal
    De Vivo, Immaculata
    PHARMACOGENETICS AND GENOMICS, 2009, 19 (03): : 239 - 243
  • [28] Characterization of a common deletion polymorphism of the UGT2B17 gene linked to UGT2B15
    Wilson, W
    de Villena, FPM
    Lyn-Cook, BD
    Chatterjee, PK
    Bell, TA
    Detwiler, DA
    Gilmore, RC
    Valladeras, IC
    Wright, CC
    Threadgill, DW
    Grant, DJ
    GENOMICS, 2004, 84 (04) : 707 - 714
  • [29] Single nucleotide polymorphisms and haplotype frequencies of UGT2B4 and UGT2B7 in a Japanese population
    Saeki, M
    Saito, Y
    Jinno, H
    Tanaka-Kagawa, T
    Ohno, A
    Ozawa, S
    Ueno, K
    Kamakura, S
    Kamatani, N
    Komamura, K
    Kitakaze, M
    Sawada, J
    DRUG METABOLISM AND DISPOSITION, 2004, 32 (09) : 1048 - 1054
  • [30] Association of UGT2B17, UGT2B7 and UGT2B28 gene copy number with prostate cancer risk
    Setlur, Sunita
    Demichelis, Francesca
    Hossain, Ruhella
    Chen, Chen
    Van Doren, Vanessa
    Stenzel, Birgit
    Oldridge, Derek
    Katabayashi, Naoki
    Schafer, Georg
    Lee, Charles
    Rubin, Mark
    Klocker, Helmut
    CANCER RESEARCH, 2009, 69
12345