A facile two-carbon ring expansion process based on the 2-cyano-1-vinylcycloalkanolsystem

被引：9
|
作者：
Shia, KS [1 ]
Jan, NW
Zhu, JL
Ly, TW
Liu, HJ
机构：
[1] Natl Tsing Hua Univ, Dept Chem, Hsinchu 300, Taiwan
[2] Univ Alberta, Dept Chem, Edmonton, AB T6G 2G2, Canada
来源：
TETRAHEDRON LETTERS | 1999年 / 40卷 / 37期
基金：
加拿大自然科学与工程研究理事会;
关键词：
ring transformations; alcohols; cyano compounds; ketones;
D O I：
10.1016/S0040-4039(99)01401-X
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Upon exposure to potassium hydride in THF in the presence of 18-crown-6, several 2-cyano-1-vinylcycloalkanol derivatives were found to undergo ring enlargement to give the corresponding gamma-cyano cycloalkanones in synthetically useful yields. (C) 1999 Elsevier Science Ltd. All rights reserved.
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页码：6753 / 6756
页数：4
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