Synthesis of 3-[alpha-(3-chloro-2-oxo-4-substituted-phenyl/furfuryl-1-azetidinyl)]-2H-1-benzopyran-2-ones and 3-[alpha-(2-substituted-phenyl/furfurylthiazolidiznyl)]-2H-1-benzopyran-2-ones as CNS-active agents

被引：0
|
作者：
Kulkarni, YD
Srivastava, D
Bishnoi, A
Dua, PR
机构：
[1] UNIV LUCKNOW,DEPT CHEM,LUCKNOW 226007,UTTAR PRADESH,INDIA
[2] CENT DRUG RES INST,DIV PHARMACOL,LUCKNOW 226007,UTTAR PRADESH,INDIA
来源：
JOURNAL OF THE INDIAN CHEMICAL SOCIETY | 1996年 / 73卷 / 4-5期
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D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Reaction of 3-substituted-phenylidine/furfurylidineamino-2H-1-benzopyran-2-ones (3a-d) with chloroacetyl chloride and thioglycolic acid affords the corresponding four-membered azetidinones (4a-d) and five-membered thiazolidinones (5a-d) respectively, All the compounds were tested for their acute toxicity, effects on gross behaviour, spontaneous motor activity (SMA), anorexigenic activity, neuroleptic activity and anticonvulsant activity, Compounds 4a and 5d exhibited C.N.S. depressant activity.
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页码：173 / 175
页数：3
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