HIV-1 RNA shedding in the female genital tract is associated with reduced quantity of Lactobacilli in clinically asymptomatic HIV-positive women

被引：6

作者：

Mane, Arati ^{[1
]}

Kulkarni, Smita ^{[1
]}

Ghate, Manisha ^{[1
]}

Risbud, Arun ^{[1
]}

Thakar, Madhuri ^{[1
]}

机构：

[1] Natl AIDS Res Inst, MIDC, Pune 411026, Maharashtra, India

来源：

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 2013年 / 75卷 / 01期

关键词：

HIV-1; Genital shedding; Lactobacilli; IMMUNODEFICIENCY-VIRUS TYPE-1; BACTERIAL VAGINOSIS;

D O I：

10.1016/j.diagmicrobio.2012.09.009

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

We quantified vaginal lactobacilli and determined their relationship with genital HIV-1 shedding and found a significant negative association between reduced quantity of lactobacilli and cervical HIV-1 viral load (r(2) = - 0.8900, P < 0.01), which may have implications of increased chances of sexual transmission of HIV-1 and genital infections. (C) 2013 Elsevier Inc. All rights reserved.

引用

页码：112 / 114

页数：3

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