Erlotinib Induces Synthetic Lethality With the Poly(ADP-Ribose) Polymerase (PARP) Inhibitor ABT-888 in Esophageal Cancer

被引：1
|
作者：
Whitley, A. C. [1 ]
Jackson, J. [1 ]
Trummell, H. [1 ]
Bonner, J. [1 ]
Yang, E. S. [1 ]
机构：
[1] Univ Alabama Birmingham, Birmingham, AL USA
来源：
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS | 2012年 / 84卷 / 03期
关键词：
D O I：
10.1016/j.ijrobp.2012.07.428
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：S165 / S166
页数：2
相关论文
共 50 条
  • [31] Phase 0 pharmacodynamic study of poly (ADP-ribose) polymerase inhibitor ABT-888 in patients with refractory solid tumors and lymphomas: Immunohistochemistry results
    Yang, S. X.
    Kummar, S.
    Rubinstein, L.
    Gutierrez, M.
    Murgo, A. J.
    Parchment, R. E.
    Nguyen, D.
    Chen, A. P.
    Tomaszewski, J. E.
    Doroshow, J. H.
    JOURNAL OF CLINICAL ONCOLOGY, 2008, 26 (15)
  • [32] A novel Poly(ADP-ribose) polymerase inhibitor, ABT-888, sensitizes malignant human cell lines to ionizing radiation under oxia and hypoxia
    Liu, S. K.
    Coackley, C.
    Bristow, R.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2007, 69 (03): : S615 - S615
  • [33] The poly(ADP-Ribose) polymerase inhibitor ABT-888 reduces radiation-induced nuclear EGFR and augments head and neck tumor response to radiotherapy
    Nowsheen, Somaira
    Bonner, James A.
    Yang, Eddy S.
    RADIOTHERAPY AND ONCOLOGY, 2011, 99 (03) : 331 - 338
  • [34] Discovery of the Poly(ADP-ribose) Polymerase (PARP) Inhibitor 2-[(R)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide (ABT-888) for the Treatment of Cancer
    Penning, Thomas D.
    Zhu, Gui-Dong
    Gandhi, Viraj B.
    Gong, Jianchun
    Liu, Xuesong
    Shi, Yan
    Klinghofer, Vered
    Johnson, Eric F.
    Donawho, Cherrie K.
    Frost, David J.
    Bontcheva-Diaz, Velitchka
    Bouska, Jennifer J.
    Osterling, Donald J.
    Olson, Amanda M.
    Marsh, Kerman C.
    Luo, Yan
    Giranda, Vincent L.
    JOURNAL OF MEDICINAL CHEMISTRY, 2009, 52 (02) : 514 - 523
  • [35] A novel poly (ADP-ribose) polymerase inhibitor, ABT-888, sensitizes malignant human cell lines to ionizing radiation under both oxia and hypoxia
    Liu, S. K.
    Coackley, C.
    Bristow, R. G.
    RADIOTHERAPY AND ONCOLOGY, 2007, 84 : S40 - S40
  • [36] A Review on Poly (ADP-ribose) Polymerase (PARP) Inhibitors and Synthetic Methodologies
    Li, Ying
    Liu, Chenfu
    Rao, Guowu
    CURRENT MEDICINAL CHEMISTRY, 2021, 28 (08) : 1565 - 1584
  • [37] Poly(ADP-ribose) polymerase (PARP) inhibitors and ovarian cancer
    Liu, Chia-Hao
    Chang, Yi
    Wang, Peng-Hui
    TAIWANESE JOURNAL OF OBSTETRICS & GYNECOLOGY, 2017, 56 (05): : 713 - 714
  • [38] Role of ABT888, a Novel Poly(ADP-Ribose) Polymerase (PARP) Inhibitor in Countering Autophagy and Apoptotic Processes Associated to Spinal Cord Injury
    Casili, Giovanna
    Campolo, Michela
    Lanza, Marika
    Filippone, Alessia
    Scuderi, Sarah
    Messina, Salvatore
    Ardizzone, Alessio
    Esposito, Emanuela
    Paterniti, Irene
    MOLECULAR NEUROBIOLOGY, 2020, 57 (11) : 4394 - 4407
  • [39] Role of ABT888, a Novel Poly(ADP-Ribose) Polymerase (PARP) Inhibitor in Countering Autophagy and Apoptotic Processes Associated to Spinal Cord Injury
    Giovanna Casili
    Michela Campolo
    Marika Lanza
    Alessia Filippone
    Sarah Scuderi
    Salvatore Messina
    Alessio Ardizzone
    Emanuela Esposito
    Irene Paterniti
    Molecular Neurobiology, 2020, 57 : 4394 - 4407
  • [40] Poly (ADP-Ribose) Polymerase Inhibitor, ABT888, Improved Cisplatin Effect in Human Oral Cell Carcinoma
    Paterniti, Irene
    Scuderi, Sarah Adriana
    Casili, Giovanna
    Lanza, Marika
    Mare, Marzia
    Giuffrida, Raffella
    Colarossi, Cristina
    Portelli, Marco
    Cuzzocrea, Salvatore
    Esposito, Emanuela
    BIOMEDICINES, 2021, 9 (07)
12345