Covalent Modifiers: An Orthogonal Approach to Drug Design

被引：279
|
作者：
Potashman, Michele H. [1 ]
Duggan, Mark E. [1 ]
机构：
[1] Amgen Inc, Dept Med Chem, Cambridge, MA 02139 USA
来源：
JOURNAL OF MEDICINAL CHEMISTRY | 2009年 / 52卷 / 05期
关键词：
GROWTH-FACTOR RECEPTOR; ACETYLGLUCOSAMINE ENOLPYRUVYL TRANSFERASE; MECHANISM-BASED INHIBITION; UDP-N-ACETYLGLUCOSAMINE; IRREVERSIBLE INHIBITORS; XANTHINE-OXIDASE; KINASE-ACTIVITY; CATHEPSIN-K; IN-VIVO; BINDING;
D O I：
10.1021/jm8008597
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
[No abstract available]
引用
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页码：1231 / 1246
页数：16
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