NMR assignment of PN2-3, a tubulin interaction subdomain of the CPAP protein

被引：3
|
作者：
Clement, Marie-Jeanne [1 ]
Savarin, Philippe [1 ]
Coutant, Jerome [1 ]
Toma, Flavio [1 ]
Curmi, Patrick [1 ]
机构：
[1] Univ Evry Val Essonne, INSERM, U829, Lab Struct Act Biomol Normales & Pathol, F-91025 Evry, France
来源：
BIOMOLECULAR NMR ASSIGNMENTS | 2008年 / 2卷 / 02期
关键词：
CPAP; Centrosome; Tubulin; Microtubules; NMR assignment;
D O I：
10.1007/s12104-008-9099-3
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
We report the NMR assignment of the PN2-3 subdomain of the CPAP protein. It has been previously shown that this motif interacts with tubulin, inhibits microtubule nucleation from the centrosome and depolymerizes taxol-stabilized microtubules.
引用
收藏
页码：115 / 117
页数：3
相关论文
共 50 条
  • [41] Protein phosphatase 2A is associated in an inactive state with microtubules through 2A1-specific interaction with tubulin
    Hiraga, A
    Tamura, S
    BIOCHEMICAL JOURNAL, 2000, 346 (02) : 433 - 439
  • [42] Investigation of 2-hydroxy-4-methoxy-2′,3′-benzochalcone binding to tubulin by using NMR and in silico docking
    Yeonjoong Yong
    Soon Young Shin
    Hyeryoung Jung
    Seunghyun Ahn
    Young Han Lee
    Dongsoo Koh
    Yoongho Lim
    Journal of the Korean Society for Applied Biological Chemistry, 2014, 57 : 693 - 698
  • [43] Investigation of 2-Hydroxy-4-methoxy-2′,3′-benzochalcone Binding to Tubulin by Using NMR and in silico Docking
    Yong, Yeonjoong
    Shin, Soon Young
    Jung, Hyeryoung
    Ahn, Seunghyun
    Lee, Young Han
    Koh, Dongsoo
    Lim, Yoongho
    JOURNAL OF THE KOREAN SOCIETY FOR APPLIED BIOLOGICAL CHEMISTRY, 2014, 57 (06): : 693 - 698
  • [44] NMR assignment of the domain 513–651 from the SARS-CoV nonstructural protein nsp3
    Amarnath Chatterjee
    Margaret A. Johnson
    Pedro Serrano
    Bill Pedrini
    Kurt Wüthrich
    Biomolecular NMR Assignments, 2007, 1 : 191 - 194
  • [45] NMR assignment of the nonstructural protein nsp3(1066-1181) from SARS-CoV
    Serrano, Pedro
    Johnson, Margaret A.
    Chatterjee, Amarnath
    Pedrini, Bill
    Wuethrich, Kurt
    BIOMOLECULAR NMR ASSIGNMENTS, 2008, 2 (02) : 135 - 138
  • [46] Efficient Stereospecific Hβ2/3 NMR Assignment Strategy for Mid-Size Proteins
    Born, Alexandra
    Henen, Morkos A.
    Nichols, Parker
    Wang, Jing
    Jones, David N.
    Vogeli, Beat
    MAGNETOCHEMISTRY, 2018, 4 (02)
  • [47] Completion axillary lymph node dissection for the identification of pN2-3 status as an indication for adjuvant CDK4/6 inhibitor treatment: a post-hoc analysis of the randomised, phase 3 SENOMAC trial
    de Boniface, Jana
    Appelgren, Matilda
    Szulkin, Robert
    Alkner, Sara
    Andersson, Yvette
    Bergkvist, Leif
    Frisell, Jan
    Gentilini, Oreste Davide
    Kontos, Michalis
    Kuehn, Thorsten
    Lundstedt, Dan
    Offersen, Birgitte Vrou
    Bagge, Roger Olofsson
    Ryden, Lisa
    Reimer, Toralf
    Sund, Malin
    Christiansen, Peer
    Tvedskov, Tove Filtenborg
    LANCET ONCOLOGY, 2024, 25 (09): : 1222 - 1230
  • [48] USE OF 2D-NMR FOR THE ASSIGNMENT OF STRUCTURE OF 1,3,2-OXAZAPHOSPHOLIDIN-2-ONES
    BOULET, CA
    TREGEAR, SJ
    HANSEN, AS
    HETEROCYCLES, 1991, 32 (11) : 2105 - 2110
  • [49] A model for the interaction of the G3-subdomain of Geobacillus stearothermophilus IF2 with the 30S ribosomal subunit
    Dongre, Ramachandra
    Folkers, Gert E.
    Gualerzi, Claudio O.
    Boelens, Rolf
    Wienk, Hans
    PROTEIN SCIENCE, 2016, 25 (09) : 1722 - 1733
  • [50] INTERDOMAIN INTERACTION IN THE 3 HELICAL BUNDLES OF PROTEIN-A STUDIED BY 2-DIMENSIONAL AND 3-DIMENSIONAL H-1-NMR
    KARIMI, A
    WRIGHT, PE
    FASEB JOURNAL, 1992, 6 (01): : A131 - A131
12345