NMR assignment of PN2-3, a tubulin interaction subdomain of the CPAP protein

被引：3
|
作者：
Clement, Marie-Jeanne [1 ]
Savarin, Philippe [1 ]
Coutant, Jerome [1 ]
Toma, Flavio [1 ]
Curmi, Patrick [1 ]
机构：
[1] Univ Evry Val Essonne, INSERM, U829, Lab Struct Act Biomol Normales & Pathol, F-91025 Evry, France
来源：
BIOMOLECULAR NMR ASSIGNMENTS | 2008年 / 2卷 / 02期
关键词：
CPAP; Centrosome; Tubulin; Microtubules; NMR assignment;
D O I：
10.1007/s12104-008-9099-3
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
We report the NMR assignment of the PN2-3 subdomain of the CPAP protein. It has been previously shown that this motif interacts with tubulin, inhibits microtubule nucleation from the centrosome and depolymerizes taxol-stabilized microtubules.
引用
收藏
页码：115 / 117
页数：3
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