Increased 68Ga-FAPI Uptake of Symptomatic Intracranial Atherosclerotic Plaque Revealed by PET/MR

被引：7
|
作者：
Yang, Qiao [1 ]
Zhang, Zongmuyu [2 ,3 ]
Li, Mingli [3 ,4 ]
Xu, Wei-Hai [2 ,3 ]
Huo, Li [1 ]
机构：
[1] Chinese Acad Med Sci & Peking Union Med Coll, Beijing Key Lab Mol Targeted Diag & Therapy Nucl, State Key Lab Complex Severe & Rare Dis, Ctr Rare Dis Res,Nucl Med Dept,Peking Union Med C, 1 Shuaifuyuan, Beijing 100730, Peoples R China
[2] Peking Union Med Coll Hosp, State Key Lab Complex Severe & Rare Dis, Dept Neurol, 1 Shuaifuyuan, Beijing 100730, Peoples R China
[3] Chinese Acad Med Sci, 1 Shuaifuyuan, Beijing 100730, Peoples R China
[4] Peking Union Med Coll Hosp, Dept Radiol, Beijing, Peoples R China
来源：
CLINICAL NUCLEAR MEDICINE | 2022年 / 47卷 / 05期
关键词：
Ga-68-FAPI; intracranial atherosclerosis; PET/MR; FIBROBLAST ACTIVATION PROTEIN;
D O I：
10.1097/RLU.0000000000004050
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
A 58-year-old man was enrolled in our Ga-68-FAPI PET/MR study for evaluation of stroke etiology. He had left thalamus and cerebellum infarction 6 months ago, and left occipital lobe infarction 2 years ago. Ga-68-FAPI PET/MR showed focal uptake along the low segment of the basilar artery. We hypothesize that the FAPI-avid plaque of basilar artery may account for the embolic events resulting in downstream infarction. Thus FAP-targeted imaging may have a potential for detection of vulnerable plaques.
引用
收藏
页码：469 / 470
页数：2
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