OBJECTIVE To evaluate prospectively the efficacy of the retroluminar transobturator male sling (AdVance (R) sling) for the functional treatment of stress urinary incontinence (SUI) after prostatectomy. PATIENTS AND METHODS A total of 137 patients with grade II-IV SUI, resulting from radical prostatectomy, were treated with the AdVance (R) sling in a prospective clinical study. In all, 11 patients were lost to follow-up. A total of 17 patients (13.5%) had additional adjuvant radiotherapy before sling implantation. Before and after sling implantation, a standardized 1-h pad test was performed and post-void residual urine, uroflowmetry, quality-of-life scores and the International Index of Erectile Function (IIEF-5) were assessed. When calculating the cure and improvement rates, 'cure' was defined as no pad use or one dry prophylactic pad; and 'improved' was defined as 1-2 pads or reduction of pads >= 50%. RESULTS After a median (range) follow-up of 27 (20-37) months, and a mean follow-up of 27.2 months, the success rate was 75.4% with 51.6% 'cured' and 23.8% 'improved'. Overall daily pad use, urine loss in the 1-h pad test and quality-of-life scores improved significantly after sling implantation. Compared with 1-year follow-up data, no worsening over time was noticed and no additional complications were seen. CONCLUSION With a mid-term follow-up, the retroluminar transobturator male sling is an effective, safe and attractive treatment option for SUI after radical prostatectomy. Results are stable over time.