Clopidogrel with Aspirin in Minor Stroke or Transient Ischemic Attack

被引:23
|
作者
Sharma, Mohit [1 ]
Khandelwal, Priyank [1 ]
机构
[1] State Univ New York Downstate Med Ctr, Brooklyn, NY USA
来源
NEW ENGLAND JOURNAL OF MEDICINE | 2013年 / 369卷 / 14期
关键词
D O I
10.1056/NEJMc1309713
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
To the Editor: Wang et al. (July 4 issue)(1) report the results of the Clopidogrel in High-Risk Patients with Acute Nondisabling Cerebrovascular Events (CHANCE) trial, which showed that in patients with transient ischemic attack (TIA) or minor stroke who can be treated within 24 hours after the onset of symptoms, the combination of clopidogrel and aspirin was superior to aspirin alone for reducing the risk of stroke in the first 90 days, with no apparent increase in the risk of hemorrhage. Recent evidence favors early carotid endarterectomy in patients with severe carotid stenosis who have neurologic symptoms similar to those ...
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收藏
页码:1375 / 1376
页数:2
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