CYP2E1-mediated mechanism of anti-genotoxicity of the broccoli constituent sulforaphane

被引:5
|
作者
Paolini, M [1 ]
Biagi, GL [1 ]
CantelliForti, G [1 ]
机构
[1] UNIV TEXAS,MED BRANCH,DEPT PREVENT MED & COMMUNITY HLTH,DIV ENVIRONM TOXICOL,GALVESTON,TX 77550
关键词
D O I
10.1093/carcin/18.7.1435
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:1435 / 1435
页数:1
相关论文
共 50 条
  • [21] Involvement of hepatic stellate cell cytoglobin in acute hepatocyte damage through the regulation of CYP2E1-mediated xenobiotic metabolism
    Teranishi, Yuga
    Matsubara, Tsutomu
    Krausz, Kristopher W.
    Le, Thi T. T.
    Gonzalez, Frank J.
    Yoshizato, Katsutoshi
    Ikeda, Kazuo
    Kawada, Norifumi
    LABORATORY INVESTIGATION, 2015, 95 (05) : 515 - 524
  • [22] Application of an Updated Physiologically Based Pharmacokinetic Model for Chloroform to Evaluate CYP2E1-Mediated Renal Toxicity in Rats and Mice
    Sasso, Alan F.
    Schlosser, Paul M.
    Kedderis, Gregory L.
    Genter, Mary Beth
    Snawder, John E.
    Li, Zheng
    Rieth, Susan
    Lipscomb, John C.
    TOXICOLOGICAL SCIENCES, 2013, 131 (02) : 360 - 374
  • [23] TRPV4 regulates inflammation and Kupffer cell activation in nonalcoholic steatohepatitis by attenuation of CYP2E1-mediated oxidative stress
    Seth, Ratanesh K.
    Das, Suvarthi
    Dattaroy, Diptadip
    Alhasson, Firas
    Bell, Phillip D.
    Michelotti, Gregory A.
    Nagarkatti, Mitzi
    Nagarkatti, Prakash
    Liedtke, Wolfgang B.
    Diehl, Anna Mae
    Chatterjee, Saurabh
    HEPATOLOGY, 2015, 62 : 1248A - 1248A
  • [24] Obesity Induces DNA Damage in Mammary Epithelial Cells Exacerbated by Acrylamide Treatment through CYP2E1-Mediated Oxidative Stress
    Walton, Brenna
    Kaplan, Noah
    Hrdlicka, Brooke
    Mehta, Kavi
    Arendt, Lisa M.
    TOXICS, 2024, 12 (07)
  • [25] Molecular mechanism of trichloroethylene-induced hepatotoxicity mediated by CYP2E1
    Ramdhan, Doni Hikmat
    Kamijima, Michihiro
    Yamada, Naoyasu
    Ito, Yuki
    Yanagiba, Yukie
    Nakamura, Daichi
    Okamura, Ai
    Ichihara, Gaku
    Aoyama, Toshifumi
    Gonzalez, Frank J.
    Nakajima, Tamie
    TOXICOLOGY AND APPLIED PHARMACOLOGY, 2008, 231 (03) : 300 - 307
  • [26] SILIBININ INHIBITS CYP2E1-MEDIATED ETHANOL METABOLISM AND ITS ASSOCIATED OXIDATIVE STRESS IN RAT AND HUMAN HEPATOCELLULAR CARCINOMA (HCC) CELLS
    Brandon-Warner, Elizabeth
    Sugg, J. Andrew
    Schrum, Laura W.
    McKillop, Iain H.
    ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, 2009, 33 (06) : 229A - 229A
  • [27] CYP2E1-mediated oxidative stress regulates HO-1 and GST expression in maneb- and paraquat-treated rat polymorphonuclear leukocytes
    Israr Ahmad
    Smriti Shukla
    Deepali Singh
    Amit Kumar Chauhan
    Vinod Kumar
    Brajesh Kumar Singh
    Devendra Kumar Patel
    Haushila Prasad Pandey
    Chetna Singh
    Molecular and Cellular Biochemistry, 2014, 393 : 209 - 222
  • [28] CYP2E1-mediated oxidative stress regulates HO-1 and GST expression in maneb- and paraquat-treated rat polymorphonuclear leukocytes
    Ahmad, Israr
    Shukla, Smriti
    Singh, Deepali
    Chauhan, Amit Kumar
    Kumar, Vinod
    Singh, Brajesh Kumar
    Patel, Devendra Kumar
    Pandey, Haushila Prasad
    Singh, Chetna
    MOLECULAR AND CELLULAR BIOCHEMISTRY, 2014, 393 (1-2) : 209 - 222
  • [29] TRPV4 attenuates Ml polarization and subsequent NASH progression by stalling CYP2E1-mediated redox toxicity via eNOS.
    Seth, Ratanesh K.
    Chandrashekaran, Varun
    Dattaroy, Diptadip
    Alhasson, Firas
    Nagarkatti, Mitzi
    Nagarkatti, Prakash
    Diehl, Anna Mae
    Liedtke, Wolfgang
    Chatterjee, Saurabh
    JOURNAL OF IMMUNOLOGY, 2017, 198 (01):
  • [30] CYP2E1-mediated oxidative stress induces COL1A2 mRNA in hepatic stellate cells and in a coculture system of Hep-G2 and stellate cells.
    Nieto, N
    Greenwel, P
    Friedman, SL
    Cederbaum, AI
    HEPATOLOGY, 1999, 30 (04) : 485A - 485A