Protection Against Vascular Leakage in Vivo by a Peptide Mimetic of the Novel Tethered Ligand Generated by Non-Canonical Cleavage of Protease Activated Receptor 1 by Activated Protein C

被引：0

作者：

Burnier, Laurent ^{[1
]}

Sinha, Ranjeet Kumar ^{[1
]}

Bouwens, Eveline A. ^{[1
]}

Griffin, John H. ^{[1
]}

Mosnier, Laurent O. ^{[1
]}

机构：

[1] Scripps Res Inst, La Jolla, CA 92037 USA

来源：

BLOOD | 2012年 / 120卷 / 21期

关键词：

D O I：

10.1182/blood.V120.21.497.497

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

497

引用

页数：2

共 32 条

[1] Protease-activated receptor 3 (PAR3) tethered-ligand peptides derived from non-canonical cleavage at Arg41 by activated protein C provide vascular barrier protective effects in vitro and in vivo
Burnier, L.
Mosnier, L. O.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2013, 11 : 63 - 63
[2] Non-Canonical Cleavage of Protease Activated Receptor 1 (PAR1) by Activated Protein C Provides Novel Insights Into the Repertoire of Cytoprotective and Proinflammatory PAR1 Signaling
Mosnier, Laurent O.
Griffin, John H.
BLOOD, 2011, 118 (21) : 247 - 248
[3] A potent peptide-mimetic antagonist for the tethered-ligand receptor protease-activated receptor-1
Derian, CK
Addo, MF
Darrow, AL
Eckardt, AJ
Hoekstra, WJ
Maryanoff, BE
McComsey, DF
Oksenberg, D
Reynolds, E
Santulli, RJ
Scarborough, RM
White, KB
Zhang, HC
Andrade-Gordon, P
THROMBOSIS AND HAEMOSTASIS, 1999, : 483 - 483
[4] Protection of vascular barrier integrity by activated protein C in murine models depends on protease-activated receptor-1
Schuepbach, Reto A.
Feistritzer, Clemens
Fernandez, Jose A.
Griffin, John H.
Riewald, Matthias
THROMBOSIS AND HAEMOSTASIS, 2009, 101 (04) : 724 - 733
[5] To be or not to be protease activated receptor-1 in activated protein C-initiated endothelial barrier protection?
Li, Shi-Sheng
CRITICAL CARE, 2007, 11 (01):
[6] To be or not to be protease activated receptor-1 in activated protein C-initiated endothelial barrier protection?
Shi Sheng Li
Critical Care, 11 (1):
[7] Activated protein C (APC) in vivo neuroprotective activity involves endothelial protein C receptor (EPCR) and protease activated receptor 1 (PAR-1)
Griffin, JH
Liu, D
Cheng, T
Fernandez, JA
Castellino, FJ
Rosen, ED
Zlokovic, BH
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2003, 23 (05) : A3 - A3
[8] To be or not to be protease activated receptor-1 in activated protein C-initiated endothelial barrier protection? Authors' response
Looney, Mark R.
Matthay, Michael A.
CRITICAL CARE, 2007, 11 (01):
[9] Biased agonism of protease-activated receptor 1 by activated protein C caused by noncanonical cleavage at Arg46
Mosnier, Laurent O.
Sinha, Ranjeet K.
Burnier, Laurent
Bouwens, Eveline A.
Griffin, John H.
BLOOD, 2012, 120 (26) : 5237 - 5246
[10] Canonical and non-canonical cleavage patterns for protease-activated receptor (PAR) 1 and 3 by factor Xa reveal novel insights into the allosteric modulation of cytoprotective PAR1 signaling by PAR3
Stavenuiter, F.
Mosnier, L. O.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2013, 11 : 347 - 347

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