Canonical and non-canonical cleavage patterns for protease-activated receptor (PAR) 1 and 3 by factor Xa reveal novel insights into the allosteric modulation of cytoprotective PAR1 signaling by PAR3

被引:0
|
作者
Stavenuiter, F. [1 ]
Mosnier, L. O. [1 ]
机构
[1] Scripps Res Inst, La Jolla, CA 92037 USA
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:347 / 347
页数:1
相关论文
共 39 条
  • [1] Non-Canonical Cleavage of Protease Activated Receptor 1 (PAR1) by Activated Protein C Provides Novel Insights Into the Repertoire of Cytoprotective and Proinflammatory PAR1 Signaling
    Mosnier, Laurent O.
    Griffin, John H.
    BLOOD, 2011, 118 (21) : 247 - 248
  • [2] Protease-activated receptor-3 (PAR3) regulates PAR1 signaling by receptor dimerization
    McLaughlin, Joseph N.
    Patterson, Myla M.
    Malik, Asrar B.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (13) : 5662 - 5667
  • [3] Humanizing the Protease-Activated Receptor (PAR) Expression Profile in Mouse Platelets by Knocking PAR1 into the Par3 Locus Reveals PAR1 Expression Is Not Tolerated in Mouse Platelets
    French, Shauna L.
    Paramitha, Antonia C.
    Moon, Mitchell J.
    Dickins, Ross A.
    Hamilton, Justin R.
    PLOS ONE, 2016, 11 (10):
  • [4] Focal ischemia induces expression of protease-activated receptor1 (PAR1) and PAR3 on microglia and enhances PAR4 labeling in the penumbra
    Henrich-Noack, P
    Riek-Burchardt, M
    Baldauf, K
    Reiser, G
    Reymann, KG
    BRAIN RESEARCH, 2006, 1070 (01) : 232 - 241
  • [5] Protease-activated Receptor 1 (PAR1) and PAR4 Heterodimers Are Required for PAR1-enhanced Cleavage of PAR4 by α-Thrombin
    Arachiche, Amal
    Mumaw, Michele M.
    de la Fuente, Maria
    Nieman, Marvin T.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2013, 288 (45) : 32553 - 32562
  • [6] Identification of a novel human thrombin receptor, protease-activated receptor 3 (PAR3)
    Kahn, ML
    Ishihara, H
    Connolly, AJ
    Coughlin, S
    THROMBOSIS AND HAEMOSTASIS, 1997, : O2460 - O2460
  • [7] Protease-activated receptor-3 (PAR-3) acts as an allosteric modulator of PAR-1 signaling via receptor dimerization
    McLaughlin, Joseph N.
    Malik, Asrar B.
    FASEB JOURNAL, 2007, 21 (06): : A1430 - A1430
  • [8] The agonist of the protease-activated receptor-1 (PAR1) but not PAR3 mimics thrombin-induced vascular endothelial growth factor release in human vascular smooth muscle cells
    T. Arisato
    K. P. Sarker
    K. Kawahara
    M. Nakata
    T. Hashiguchi
    M. Osame
    I. Kitajima
    I. Maruyama
    Cellular and Molecular Life Sciences CMLS, 2003, 60 : 1716 - 1724
  • [9] The agonist of the protease-activated receptor-1 (PAR1) but not PAR3 mimics thrombin-induced vascular endothelial growth factor release in human vascular smooth muscle cells
    Arisato, T
    Sarker, KP
    Kawahara, K
    Nakata, M
    Hashiguchi, T
    Osame, M
    Kitajima, I
    Maruyama, I
    CELLULAR AND MOLECULAR LIFE SCIENCES, 2003, 60 (08) : 1716 - 1724
  • [10] FVIIa (Factor VIIa) Induces Biased Cytoprotective Signaling in Mice Through the Cleavage of PAR (Protease-Activated Receptor)-1 at Canonical Arg41 (Arginine41) Site
    Kondreddy, Vijay
    Pendurthi, Usha R.
    Xu, Xiao
    Griffin, John H.
    Rao, L. Vijaya Mohan
    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2020, 40 (05) : 1275 - 1288