Adaptor Protein Lnk Binds to and Inhibits Normal and Leukemic FLT3

被引：0
|
作者：
Lin, Dechen [1 ]
Yin, Tong [1 ]
Koren-Michowitz, Maya [1 ]
Ding, Ling-Wen [2 ]
Gueller, Saskia [3 ]
Gery, Sigal [1 ]
Tabayashi, Takayuki [1 ]
Bergholz, Ulla [4 ]
Kazi, Julhash [5 ]
Ronnstrand, Lars [5 ]
Stocking, Carol [4 ]
Koeffler, Phillip [1 ]
机构：
[1] Univ Calif Los Angeles, Cedars Sinai Med Ctr, Sch Med, Div Hematol Oncol, Los Angeles, CA 90048 USA
[2] Canc Sci Inst Singapore, Singapore, Singapore
[3] Goethe Univ Frankfurt, Dept Med, D-60054 Frankfurt, Germany
[4] Heinrich Pette Inst, Hamburg, Germany
[5] Lund Univ, Skane Univ Hosp, Malmo, Sweden
来源：
BLOOD | 2012年 / 120卷 / 21期
关键词：
D O I：
10.1182/blood.V120.21.1312.1312
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
1312
引用
收藏
页数：2
相关论文
共 50 条
  • [41] Regulation of FLT3 and its ligand in normal hematopoietic progenitor cells
    Weisel, Katja C.
    Yildirim, Sedat
    Schweikle, Eric
    Kanz, Lothar
    Moehle, Robert
    ANNALS OF HEMATOLOGY, 2009, 88 (03) : 203 - 211
  • [42] THE ROLE OF FLT3: ITD IN ACUTE MYELOID LEUKAEMIA WITH NORMAL CYTOGENETICS
    Indran, T.
    Hahn, U.
    INTERNAL MEDICINE JOURNAL, 2012, 42 : 18 - 18
  • [43] TP-0184 inhibits FLT3/ACVR1 to overcome FLT3 inhibitor resistance and hinder AML growth synergistically with venetoclax
    Anudishi Tyagi
    Appalaraju Jaggupilli
    Stanley Ly
    Bin Yuan
    Fouad El-Dana
    Venkatesh L. Hegde
    Vivek Anand
    Bijender Kumar
    Mamta Puppala
    Zheng Yin
    Stephen T. C. Wong
    Alexis Mollard
    Hariprasad Vankayalapati
    Jason M. Foulks
    Steven L. Warner
    Naval Daver
    Gautam Borthakur
    V. Lokesh Battula
    Leukemia, 2024, 38 : 82 - 95
  • [44] Regulation of FLT3 and its ligand in normal hematopoietic progenitor cells
    Katja C. Weisel
    Sedat Yildirim
    Eric Schweikle
    Lothar Kanz
    Robert Möhle
    Annals of Hematology, 2009, 88 : 203 - 211
  • [45] FLT3 ligand administration inhibits tumor growth in murine melanoma and lymphoma
    Esche, C
    Subbotin, VM
    Maliszewski, C
    Lotze, MT
    Shurin, MR
    CANCER RESEARCH, 1998, 58 (03) : 380 - 383
  • [46] Plm-102, a Next Generation FLT3 Inhibitor, Shows Potent Anti-Leukemic Activity on Resistance to Gilteritinib in FLT3 Mutated Acute Myeloid Leukemia
    Lee, Jae-Seon
    Park, Min Ji
    Sun, Ningning
    Park, Jin-Hee
    Oh, Su-jin
    Moon, Miran
    Kim, Myung Jin
    Jang, Soo Yeon
    Kim, Yong-Chul
    BLOOD, 2023, 142
  • [47] FLT3/D835 mutation and inversion of chromosome 16 in leukemic transformation of myelofibrosis
    Colovic, Milica
    Jurisic, Vladimir
    Pavlovic, Sonja
    Terzic, TaIjana
    Colovic, Natasa
    EUROPEAN JOURNAL OF INTERNAL MEDICINE, 2006, 17 (06) : 434 - 435
  • [48] Constitutive FLT3 activation results in specific changes in gene expression in myeloid leukemic cells
    Kim, KT
    Baird, K
    Davis, S
    Levis, M
    Piloto, O
    Li, L
    Chen, PL
    Meltzer, P
    Small, D
    BLOOD, 2004, 104 (11) : 316A - 316A
  • [49] Effects of flt3 ligand on acute myeloid and lymphocytic leukemic blast cells from children
    McKenna, HJ
    Smith, FO
    Brasel, K
    Hirschstein, D
    Bernstein, ID
    Williams, DE
    Lyman, SD
    EXPERIMENTAL HEMATOLOGY, 1996, 24 (02) : 378 - 385
  • [50] Flt3 internal tandem duplications cooperate with Wnt signaling in leukemic signal transduction.
    Tickenbrock, L
    Schwable, J
    Wiedehage, M
    Steffen, B
    Choudhary, C
    Berdel, WE
    Muller-Tidow, C
    Serve, H
    BLOOD, 2004, 104 (11) : 234A - 235A
12345