Recent Advances in Synthetic Routes to Azacycles

被引:4
|
作者
Nguyen, Anh Thu [1 ]
Kim, Hee-Kwon [1 ,2 ]
机构
[1] Jeonbuk Natl Univ, Med Sch & Hosp, Dept Nucl Med, Jeonju 54907, South Korea
[2] Jeonbuk Natl Univ, Jeonbuk Natl Univ Hosp, Res Inst Clin Med, Biomed Res Inst, Jeonju 54907, South Korea
来源
MOLECULES | 2023年 / 28卷 / 06期
基金
新加坡国家研究基金会;
关键词
azacycles; N-heterocycles; heterocyclic synthesis; ARYL-SUBSTITUTED AZACYCLES; AQUEOUS N-HETEROCYCLIZATION; ELECTRONIC-STRUCTURE; MEDIATED SYNTHESIS; AZOMETHINE YLIDES; 3+2 CYCLOADDITION; PRIMARY AMINES; AMINATION; CYCLIZATION; INHIBITORS;
D O I
10.3390/molecules28062737
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A heterocycle is an important structural scaffold of many organic compounds found in pharmaceuticals, materials, agrochemicals, and biological processes. Azacycles are one of the most common motifs of a heterocycle and have a variety of applications, including in pharmaceuticals. Therefore, azacycles have received significant attention from scientists and a variety of methods of synthesizing azacycles have been developed because their efficient synthesis plays a vital role in the production of many useful compounds. In this review, we summarize recent approaches to preparing azacycles via different methods as well as describe plausible reaction mechanisms.
引用
收藏
页数:44
相关论文
共 50 条
  • [42] Silylated vinyloxiranes -: Recent advances and synthetic applications
    Marion, F
    Calvet, S
    Marié, JC
    Courillon, C
    Malacria, M
    [J]. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2006, 2006 (02) : 453 - 462
  • [43] Recent advances in the preparation of synthetic analogs of methanobactin
    Rabinovich, Daniel
    [J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2014, 247
  • [44] RECENT ADVANCES IN THE SYNTHETIC USES OF CHLOROCARBONYL ISOCYANATE
    KAMAL, A
    [J]. HETEROCYCLES, 1990, 31 (07) : 1377 - 1391
  • [45] Recent advances in synthetic micro reaction technology
    Watts, Paul
    Wiles, Charlotte
    [J]. CHEMICAL COMMUNICATIONS, 2007, (05) : 443 - 467
  • [46] Insights into the Recent Synthetic Advances of Organoselenium Compounds
    Makhal, Priyanka N.
    Nandi, Arijit
    Kaki, Venkata Rao
    [J]. CHEMISTRYSELECT, 2021, 6 (04): : 663 - 679
  • [47] Recent synthetic advances in the nucleophilic amination of benzenes
    Belfield, AJ
    Brown, GR
    Foubister, AJ
    [J]. TETRAHEDRON, 1999, 55 (38) : 11399 - 11428
  • [48] Heterometallic grids: synthetic strategies and recent advances
    Yang, Qianqian
    Tang, Jinkui
    [J]. DALTON TRANSACTIONS, 2019, 48 (03) : 769 - 778
  • [49] Recent advances in engineering synthetic biomolecular condensates
    Wan, Li
    Ke, Juntao
    Zhu, Yingying
    Zhang, Wenli
    Mu, Wanmeng
    [J]. BIOTECHNOLOGY ADVANCES, 2024, 77
  • [50] Recent Synthetic Advances on -Extended Carbon Nanohoops
    Luan, Yi
    Cong, Huan
    [J]. SYNLETT, 2017, 28 (12) : 1383 - 1388