Current development and clinical applications of artificial anal sphincter

被引:2
|
作者
Wang, Minghui [1 ,2 ,3 ]
Liu, Yunlong [1 ,2 ]
Nong, Qingjun [1 ,2 ]
Yu, Hongliu [1 ,2 ]
机构
[1] Univ Shanghai Sci & Technol, Shanghai, Peoples R China
[2] Shanghai Engn Res Ctr Assist Devices, Shanghai, Peoples R China
[3] Univ Shanghai Sci & Technol, Sch Hlth Sci & Engn, Shanghai 200093, Peoples R China
基金
中国国家自然科学基金;
关键词
Artificial anal sphincter; Biomechanical compatibility; Constant force; Fecal incontinence; Shape memory alloy; Superelasticity; SEVERE FECAL INCONTINENCE; SACRAL NERVE-STIMULATION; LONG-TERM EXPERIENCE; QUALITY-OF-LIFE; BOWEL SPHINCTER; IN-VITRO; BIOMECHANICAL COMPATIBILITY; SANDWICH STRUCTURE; SYSTEM-GASS; MANAGEMENT;
D O I
10.1080/17434440.2023.2219000
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
IntroductionFecal incontinence is a common chronic disease, which not only brings inconvenience to the lives of patients, but also causes great psychological harm to patients. Artificial anal sphincter is an innovative method that may treat fecal incontinence, and now has been clinically applied.Areas coveredThis article will review recent developments in mechanisms and clinical applications of artificial anal sphincter. The current results of clinical trials show that the implantation of artificial sphincter will cause morphological changes of surrounding tissues, and related biomechanical imbalance will lead to the loss of effectiveness of the device and various complications. In terms of safety, postoperative patients suffer from various complications such as infection, corrosion, tissue ischemia, mechanical failure, and difficulty in emptying. In terms of effectiveness, there is currently no long-term research data to prove that the implanted device can maintain a long-term functional state.Expert opinionThe key issue for the safety and effectiveness of implantable devices is the biomechanical compatibility of implantable devices was proposed. Based on the superelasticity of shape memory alloy, this article proposes a new type of constant force artificial sphincter device, which provides a new direction for solving the clinical application of artificial anal sphincter.
引用
收藏
页码:537 / 548
页数:12
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