Small intestinal protein sensing pathways regulate food intake and glucose homeostasis

被引：0
|
作者：
Lam, Tony K. T. [1 ]
机构：
[1] Toronto Gen Hosp Res Inst, Toronto, ON, Canada
来源：
NATURE METABOLISM | 2024年 / 6卷 / 01期
关键词：
D O I：
10.1038/s42255-023-00947-z
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Calcium sensing receptor (CaSR) and peptide transporter 1 (PepT1) have been implicated in protein sensing in the gut, although the mechanisms are poorly understood. We find that, in the small intestine, CasR and PepT1 are necessary for protein sensing to regulate gut peptide release, feeding and glucose tolerance in rats in vivo.
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页码：14 / 15
页数：2
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