Successful Treatment of Psoriasis Combined with Bullous Pemphigoid with Dupilumab: A Case Report

被引:2
|
作者
Liu, Jing-Hua [1 ,2 ]
Gao, Qian [1 ]
Ma, Wen-Yi [1 ]
Cheng, Zi-Lin [1 ]
Luo, Na-Na [1 ]
Hao, Ping-Sheng [1 ,3 ]
机构
[1] Hosp Chengdu Univ Tradit Chinese Med, Dept Dermatol, Chengdu, Sichuan, Peoples R China
[2] Dalian Dermatosis Hosp, Dalian, Liaoning, Peoples R China
[3] Hosp Chengdu Univ Tradit Chinese Med, 39 Shi er qiao Rd, Chengdu, Sichuan Provinc, Peoples R China
关键词
autoimmune bullous diseases; dupilumab; biologics; comorbidity; Chinese herbal compounds; USTEKINUMAB; THERAPY; PATIENT;
D O I
10.2147/CCID.S415019
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Psoriasis is an immune-mediated chronic inflammatory disease that can be combined with complications such as diabetes, cardiovascular disease, obesity, and kidney disease. The comorbidity of psoriasis with autoimmune bullous diseases (AIBD) has been reported previously in several cases, the most frequent of which is bullous pemphigoid (BP). The underlying mechanisms of psoriasis with BP are not clear and there are no uniform treatment criteria. Based on previous case reports, the coexistence of psoriasis and BP may be related to inflammatory activity, medications, phototherapy, and infection. We report a case of a psoriasis patient who developed BP after taking Chinese herbal compounds and was successfully treated with dupilumab, which is the first reported case of applying dupilumab to treat psoriasis with BP comorbidities.
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页码:1583 / 1587
页数:5
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