Current Considerations in the Diagnosis and Treatment of Circadian Rhythm Sleep-Wake Disorders in Children

被引：0

作者：

Witt, Rochelle M. ^{[1
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Byars, Kelly C. ^{[2
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Decker, Kristina ^{[2
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Dye, Thomas J. ^{[1
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Riley, Jessica M. ^{[4
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]}

Simmons, Danielle ^{[2
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Smith, David F. ^{[2
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]}

机构：

[1] Cincinnati Childrens Hosp Med Ctr, Div Child Neurol, Cincinnati, OH USA

[2] Cincinnati Childrens Hosp Med Ctr, Div Pulm & Sleep Med, Cincinnati, OH USA

[3] Cincinnati Childrens Hosp Med Ctr, Sleep Ctr, Cincinnati, OH USA

[4] Cincinnati Childrens Hosp Med Ctr, Ctr Circadian Med, Cincinnati, OH USA

[5] Univ Cincinnati, Coll Med, Dept Pediat, Cincinnati, OH USA

[6] Cincinnati Childrens Hosp Med Ctr, Div Behav Med & Clin Psychol, Cincinnati, OH USA

[7] Cincinnati Childrens Hosp Med Ctr, Div Human Genet, Cincinnati, OH USA

[8] Cincinnati Childrens Hosp Med Ctr, Div Pediat Otolaryngol Head & Neck Surg, Cincinnati, OH USA

[9] Univ Cincinnati, Coll Med, Dept Otolaryngol Head & Neck Surg, Cincinnati, OH USA

[10] Univ Cincinnati, Cincinnati Childrens Hosp Med Ctr, Dept Otolaryngol Head & Neck Surg, Div Pediat Otolaryngol,Coll Med,Pulm Med, Cincinnati, OH 45229 USA

[11] Univ Cincinnati, Cincinnati Childrens Hosp Med Ctr, Sleep Ctr, Dept Otolaryngol Head & Neck Surg,Coll Med, Cincinnati, OH 45229 USA

来源：

SEMINARS IN PEDIATRIC NEUROLOGY | 2023年 / 48卷

关键词：

LIGHT MELATONIN ONSET; PHASE RESPONSE CURVE; SMITH-MAGENIS SYNDROME; BODY-TEMPERATURE; BRIGHT-LIGHT; AMERICAN ACADEMY; 2-PROCESS MODEL; ACTION SPECTRUM; BLIND PATIENTS; YOUNG-ADULTS;

D O I：

10.1016/j.spen.2023.101091

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Circadian Rhythm Sleep-Wake Disorders (CRSWDs) are important sleep disorders whose unifying feature is a mismatch between the preferred or required times for sleep and wakefulness and the endogenous circadian drives for these. Their etiology, presentation, and treatment can be different in pediatric patients as compared to adults. Evaluation of these disorders must be performed while viewed through the lens of a patient's comorbid conditions. Newer methods of assessment promise to provide greater diagnostic clarity and critical insights into how circadian physiology affects overall health and disease states. Effective clinical management of CRSWDs is multimodal, requiring an integrated approach across disciplines. Therapeutic success depends upon appropriately timed nonpharmacologic and pharmacologic interventions. A better understanding of the genetic predispositions for and causes of CRSWDs has led to novel clinical opportunities for diagnosis and improved therapeutics.

引用

页数：8

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