Recent Advances in Microbial Metabolic Engineering for Production of Natural Phenolic Acids

被引：1
|
作者：
Li, Jin [1 ]
Lu, Xiumin [1 ]
Zou, Xiang [2 ]
Ye, Bang-Ce [3 ]
机构：
[1] Chongqing Univ Technol, Coll Pharm & Bioengn, Chongqing 400054, Peoples R China
[2] Southwest Univ, Coll Pharmaceut Sci, Chongqing 400715, Peoples R China
[3] East China Univ Sci & Technol, Inst Engn Biol & Hlth, Lab Biosyst & Microanal, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China
来源：
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | 2024年 / 72卷 / 09期
关键词：
phenolicacids; metabolic engineering; shikimatepathway; dynamic regulation; P-COUMARIC ACID; PSEUDOMONAS-PUTIDA S12; HIGH-LEVEL PRODUCTION; VANILLIC ACID; CINNAMIC ACID; CORYNEBACTERIUM-GLUTAMICUM; ESCHERICHIA-COLI; EFFICIENT BIOSYNTHESIS; GALLIC ACID; PATHWAY;
D O I：
10.1021/acs.jafc.3c07658
中图分类号：
S [农业科学];
学科分类号：
09 ;
摘要：
Phenolic acids are important natural bioactive compounds with varied physiological functions. They are extensively used in food, pharmaceutical, cosmetic, and other chemical industries and have attractive market prospects. Compared to plant extraction and chemical synthesis, microbial fermentation for phenolic acid production from renewable carbon sources has significant advantages. This review focuses on the structural information, physiological functions, current applications, and biosynthesis pathways of phenolic acids, especially advances in the development of metabolically engineered microbes for the production of phenolic acids. This review provides useful insights concerning phenolic acid production through metabolic engineering of microbial cell factories.
引用
收藏
页码：4538 / 4551
页数：14
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