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Androgenic-anabolic steroid abuse trend and management: A prospective, cross-sectional, questionnaire-based survey
被引:3
|作者:
Al Hashimi, Manaf
[1
,2
]
Farahat, Yasser
[3
]
Kandil, Hussein
[4
]
Al Khalidi, Ismail
[5
]
机构:
[1] Burjeel Hosp, Urol Dept, Abu Dhabi, U Arab Emirates
[2] Khalifa Univ, Coll Med & Hlth Sci, Abu Dhabi, U Arab Emirates
[3] Shaikh Khalifa Hosp, Urol Dept, Umm Al Quwain, U Arab Emirates
[4] Fakih IVF Fertil Ctr, Abu Dhabi, U Arab Emirates
[5] Al Garhoud Hosp, Urol Dept, Dubai, U Arab Emirates
关键词:
androgenic anabolic steroid;
andrology;
reproductive health;
urology;
INDUCED HYPOGONADISM;
SPERMATOGENESIS;
CONSEQUENCES;
RECOVERY;
THERAPY;
D O I:
10.1002/hsr2.1032
中图分类号:
R1 [预防医学、卫生学];
学科分类号:
1004 ;
120402 ;
摘要:
Background and AimsAndrogenic-anabolic steroid (AAS) abuse is a global health concern, studies revealing an increasing trend of abuse and deleterious effects on reproductive health. Unfortunately, there is no consensus about management pathways due to the lack of specific guidelines. MethodsA prospective study, multicentre, online survey, composed of 30 questions, was conducted to investigate the current trend of AAS abuse and the management followed by practitioners from different specialities dealing with this condition. ResultsA total of 151 respondents were included. The majority were general urologists (68.21%), andrologists (22.51%), and endocrinologists (9.28%). An increasing trend of AAS abuse was noticed by 90.73% of participants mostly in young age populations. Most of AAS abusers were presented with infertility (64.24%) and erectile dysfunction (59.60%), and their investigations showed abnormal semen analysis (77.48%), abnormal hormones (follicle-stimulating hormone, luteinizing hormone, testosterone, and estradiol) (94.70%), and reduction in testicular size (50.33%). Most of respondents expected: the need of long duration for spontaneous recovery (6-12 months), relapse of AAS abuse in one-third of patients, less knowledge about the adverse effects (39.74%), and risk of drug dependence (54.30%). Immediate treatment was the most offered plan of management (44.37%) followed by a waiting spontaneous recovery (32.45%), while the remaining would refer the patients to an either endocrinologist or andrologist. The treating physicians did not follow specific guidelines and most of participants (44.44%) reverted to their personal experience in the management. ConclusionsOur study revealed an increasing trend of AAS abuse, deleterious effects of AAS use on reproductive health, and lack of consensuses among the treating physicians regarding the management of related adverse effects. Our study could be considered a call to the scientific bodies to have more studies, establish guidelines for management, and to have better awareness of this serious public health concern.
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