Novel Treatments for Obesity: Implications for Cancer Prevention and Treatment

被引：4

作者：

Cuttica, Carla Micaela ^{[1
]}

Briata, Irene Maria ^{[2
]}

DeCensi, Andrea ^{[2
,3
]}

机构：

[1] EO Osped Galliera, Endocrine Unit, I-16128 Genoa, Italy

[2] EO Osped Galliera, Div Med Oncol, I-16128 Genoa, Italy

[3] Queen Mary Univ London, Wolfson Inst Populat Hlth, Barts & London Sch Med & Dent, London E1 2AD, England

来源：

NUTRIENTS | 2023年 / 15卷 / 17期

关键词：

obesity; neoplasms; anti-obesity agents; glucagon-like peptide 1; liraglutide; weight loss; GLP-1 RECEPTOR AGONIST; BREAST-CANCER; PROSTATE-CANCER; INHIBITS GROWTH; CLINICAL ENDOCRINOLOGISTS; AMERICAN ASSOCIATION; AUGMENTS APOPTOSIS; WEIGHT-LOSS; METFORMIN; LIRAGLUTIDE;

D O I：

10.3390/nu15173737

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

It is now established that obesity is related to a higher incidence of cancer during a lifespan. The effective treatment of obesity opens up new perspectives in the treatment of a relevant modifiable cancer risk factor. The present narrative review summarizes the correlations between weight loss in obesity and cancer. The current knowledge between obesity treatment and cancer was explored, highlighting the greatest potential for its use in the treatment of cancer in the clinical setting. Evidence for the effects of obesity therapy on proliferation, apoptosis, and response to chemotherapy is summarized. While more studies, including large, long-term clinical trials, are needed to adequately evaluate the relationship and durability between anti-obesity treatment and cancer, collaboration between oncologists and obesity treatment experts is increasingly important.

引用

页数：14

共 50 条

[41] Treatment of obesity and its prevention
Böhler, T
Wabitsch, M
MONATSSCHRIFT KINDERHEILKUNDE, 2004, 152 (08) : 856 - +
[42] Treatment and prevention of childhood obesity
Faki, I.
Sekouli, I.
Katsaras, G.
Karachrysafi, S.
Papamitsou, T.
ARCHIVES OF HELLENIC MEDICINE, 2024, 41 (06): : 740 - 747
[43] Androgen excess in breast cancer development: implications for prevention and treatment
Secreto, Giorgio
Girombelli, Alessandro
Krogh, Vittorio
ENDOCRINE-RELATED CANCER, 2019, 26 (02) : R81 - R94
[44] Poking at probiotic mechanisms and microbial implications in cancer prevention and treatment
Sun, Jun
GUT, 2024, 73 (09) : 1408 - 1409
[45] PROTEIN-KINASE-C - IMPLICATIONS FOR CANCER PREVENTION AND TREATMENT
WEINSTEIN, IB
MOUNT SINAI JOURNAL OF MEDICINE, 1992, 59 (05): : 387 - 390
[46] Inflammation and breast cancer: Understanding the interplay and implications for prevention and treatment
Ogungbola, Opeyemi O.
Ejeh, Samuel O.
Odeh, Jane
Omoniyi, Olajumoke R.
Akomolafe, Abayomi A.
Abudu, Emmanuel K.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 2024, 33 (09)
[47] Implications for heart failure prevention and treatment of cardiotoxicity in the cancer patient
Lewis, Connie M.
HEART & LUNG, 2013, 42 (01): : 4 - 4
[48] Developing novel targets for treatment and prevention of oral cancer
Boyle, J
ORAL ONCOLOGY, 2005, 1 (01) : 55 - 55
[49] Microbiome and Prostate Cancer: A Novel Target for Prevention and Treatment
Kustrimovic, Natasa
Bombelli, Raffaella
Baci, Denisa
Mortara, Lorenzo
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (02)
[50] Metformin: A Novel but Controversial Drug in Cancer Prevention and Treatment
Sui, Xinbing
Xu, Yinghua
Wang, Xian
Han, Weidong
Pan, Hongming
Xiao, Mang
MOLECULAR PHARMACEUTICS, 2015, 12 (11) : 3783 - 3791

← 1 2 3 4 5 →