Ni-Catalyzed 1,2-Alkyl Borylation and Silylation of Allenes En Route to [1,3]-Bis-Organometallic Reagents

被引：1

作者：

Velasco-Rubio, Alvaro ^{[1
]}

Cong, Fei ^{[1
]}

Tian, Yubiao ^{[1
,2
]}

Martin, Ruben ^{[1
,3
]}

机构：

[1] Barcelona Inst Sci & Technol, Inst Chem Res Catalonia ICIQ, Tarragona 43007, Spain

[2] Univ Rovira & Virgili, Dept Quim Analit & Quim Organ, Tarragona 43007, Spain

[3] ICREA, Barcelona 08010, Spain

来源：

ORGANIC LETTERS | 2023年 / 25卷 / 51期

关键词：

ENANTIOSELECTIVE DIBORATION; REGIOSELECTIVE SILABORATION; ASYMMETRIC SILABORATION; BORONIC ESTERS; IODIDES; ALKYNES;

D O I：

10.1021/acs.orglett.3c03574

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A nickel-catalyzed multicomponent reaction that rapidly and reliably accesses [1,3]-bis-organometallic reagents from allenes is reported. The protocol exhibits a predictable regioselectivity pattern that enables the incorporation of B,B-(Si) fragments across the allene backbone under mild conditions, thus offering a complementary platform for accessing polyorganometallic reagents possessing both sp(2) and sp(3) hybridization from readily available precursors.

引用

页码：9147 / 9152

页数：6

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