In vitro modelling of intraneuronal tau aggregation in a hiPSC-derived co-culture system of neurons, astrocytes and microglia

被引：0
|
作者：
Roewe, J. [1 ]
Riesinger, Y. [1 ]
Lee, H. C. [1 ]
Bahnassawy, L. [1 ]
Schoendorf, D. [1 ]
Sahin, E. [1 ]
Singh, S. [1 ]
Paul, Y.
Thomanetz, V. [1 ]
Untucht, C. [1 ]
Soper, J. [3 ]
Wachter, A. [2 ]
Ried, J. S. [2 ]
Ehrnhoefer, D. [1 ]
Talanian, R. V. [3 ]
Biber, K. [1 ]
Wassmer, T. [1 ]
Cik, M. [1 ]
Reinhardt, P. [1 ]
机构：
[1] AbbVie Deutschland GmbH & Co KG, Neurosci Discovery, Ludwigshafen, Germany
[2] AbbVie Deutschland GmbH & Co KG, Genom Res Ctr, Ludwigshafen, Germany
[3] AbbVie Inc, Fdn Neurosci Ctr, Cambridge, MA USA
来源：
GLIA | 2023年 / 71卷
关键词：
D O I：
暂无
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
T11-097C
引用
收藏
页码：E628 / E628
页数：1
相关论文
共 39 条
  • [31] Establishment of a novel in vitro co-culture system of enteric neurons and Caco-2 cells for evaluating the effect of enteric nervous system on transepithelial transport of drugs
    Maruyama, Masato
    Yoshikata, Minami
    Sakaguchi, Mana
    Wakushima, Shizuka
    Higaki, Kazutaka
    INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2023, 633
  • [32] Microglia-mediated drug substance transfer promotes chemoresistance in brain tumors: insights from an in vitro co-culture model using GCV/Tk prodrug system
    Wu, Sheng-Yan
    Yu, Wen-Jui
    Chien, Ting-Yi
    Ren, Yu-An
    Chen, Chi-Shuo
    Chiang, Chi-Shiun
    CANCER CELL INTERNATIONAL, 2024, 24 (01)
  • [33] Microglia-mediated drug substance transfer promotes chemoresistance in brain tumors: insights from an in vitro co-culture model using GCV/Tk prodrug system
    Sheng-Yan Wu
    Wen-Jui Yu
    Ting-Yi Chien
    Yu-An Ren
    Chi-Shuo Chen
    Chi-Shiun Chiang
    Cancer Cell International, 24
  • [34] The Effect of Conditioned Media of Stem Cells Derived from Lipoma and Adipose Tissue on Macrophages' Response and Wound Healing in Indirect Co-culture System In Vitro
    Stojanovic, Sanja
    Najman, Stevo
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019, 20 (07)
  • [35] Human monocyte-derived dendritic cells from leukoreduction system chambers after plateletpheresis are functional in an in vitro co-culture assay with intestinal epithelial cells
    Tiscornia, Ines
    Sanchez-Martins, Viviana
    Hernandez, Ana
    Bollati-Fogolin, Mariela
    JOURNAL OF IMMUNOLOGICAL METHODS, 2012, 384 (1-2) : 164 - 170
  • [36] In vitro differentiation of bone marrow stromal cells into neurons and glial cells and differential protein expression in a two-compartment bone marrow stromal cell/neuron co-culture system
    Qi, Xu
    Shao, Ming
    Peng, Haisheng
    Bi, Zhenggang
    Su, Zhiqiang
    Li, Hulun
    JOURNAL OF CLINICAL NEUROSCIENCE, 2010, 17 (07) : 908 - 913
  • [37] Development of a novel co-culture system using human pancreatic cancer cells and human iPSC-derived stellate cells to mimic the characteristics of pancreatic ductal adenocarcinoma in vitro
    Kometani, Tatsuya
    Kamo, Koki
    Kido, Taketomo
    Hiraoka, Nobuyoshi
    Chibazakura, Taku
    Unno, Kenji
    Sekine, Keisuke
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2023, 658 : 1 - 9
  • [38] Sertoli cell-mediated differentiation of male germ cell-like cells from human umbilical cord Wharton's jelly-derived mesenchymal stem cells in an in vitro co-culture system
    Xie, Lichun
    Lin, Limin
    Tang, Qiuliu
    Li, Weizhong
    Huang, Tianhua
    Huo, Xiao
    Liu, Xiaoshan
    Jiang, Jikai
    He, Guyu
    Ma, Lian
    EUROPEAN JOURNAL OF MEDICAL RESEARCH, 2015, 20
  • [39] Sertoli cell-mediated differentiation of male germ cell-like cells from human umbilical cord Wharton’s jelly-derived mesenchymal stem cells in an in vitro co-culture system
    Lichun Xie
    Limin Lin
    Qiuliu Tang
    Weizhong Li
    Tianhua Huang
    Xiao Huo
    Xiaoshan Liu
    Jikai Jiang
    Guyu He
    Lian Ma
    European Journal of Medical Research, 20
1234