Transcatheter Therapy for Tricuspid Regurgitation - First Act

Severe tricuspid regurgitation is associated with impaired quality of life and poor survival.1 The condition is managed medically with diuretic agents; surgery is of limited use, since many patients have a variety of coexisting conditions that increase surgical risk. Current U.S. and European society guidelines recommend tricuspid-valve surgery primarily in conjunction with left heart surgery or in symptomatic patients with severe tricuspid regurgitation and right ventricular dilatation who do not have severe right ventricular dysfunction.2,3 Whether the available treatment options improve the prognosis of patients with severe isolated tricuspid regurgitation has not been addressed specifically in randomized trials. As a. © 2023 Massachusetts Medical Society.