Moesin-induced adriamycin resistance through IL-6/MSN/STAT3 axis and therapeutic efficacy of atovaquone in chemotherapy resistant triple-negative breast cancer

被引:0
|
作者
Lee, Cheng Hyun
Kim, Da Sol
Park, Soo Young
Ryu, Han Suk
机构
关键词
D O I
10.1158/1538-7445.AM2023-2774
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
2774
引用
收藏
页数:2
相关论文
共 50 条
  • [21] Dual inhibition of CDK4/6 and IL-6 pathways as a novel therapeutic approach for triple-negative breast cancer cells
    Caroland, Kailey
    Shi, Changyou
    Lo, Hui-Wen
    Lin, Jiayuh
    CANCER RESEARCH, 2024, 84 (06)
  • [22] Nifuroxazide boosts the anticancer efficacy of palbociclib-induced senescence by dual inhibition of STAT3 and CDK2 in triple-negative breast cancer
    Xianzhe Wang
    Wei Shi
    Xumei Wang
    Jin-Jian Lu
    Ping He
    Hongjie Zhang
    Xiuping Chen
    Cell Death Discovery, 9
  • [23] Nifuroxazide boosts the anticancer efficacy of palbociclib-induced senescence by dual inhibition of STAT3 and CDK2 in triple-negative breast cancer
    Wang, Xianzhe
    Shi, Wei
    Wang, Xumei
    Lu, Jin-Jian
    He, Ping
    Zhang, Hongjie
    Chen, Xiuping
    CELL DEATH DISCOVERY, 2023, 9 (01)
  • [24] Design, Synthesis, and Biological Activity of Marinacarboline Analogues as STAT3 Pathway Inhibitors for Docetaxel-Resistant Triple-Negative Breast Cancer
    Byun, Woong Sub
    Lim, Hyewon
    Hong, Junhwa
    Bae, Eun Seo
    Lee, Seok Beom
    Kim, Younggwan
    Lee, Jeeyeon
    Lee, Sang Kook
    Hong, Suckchang
    JOURNAL OF MEDICINAL CHEMISTRY, 2023, 66 (04) : 3106 - 3133
  • [25] Nuclear translocation of thioredoxin-1 promotes colorectal cancer development via modulation of the IL-6/STAT3 signaling axis through interaction with STAT3
    Wu, Aihua
    Fang, Daoquan
    Liu, Yangyang
    Shi, Xiaomeng
    Zhong, Zuyue
    Zhou, Baojian
    Ye, Lechi
    Sun, Xuecheng
    Jiang, Lei
    THERANOSTICS, 2023, 13 (14): : 4730 - 4744
  • [26] Targeting the IL-6/STAT3 Signalling Cascade to Reverse Tamoxifen Resistance in Estrogen Receptor Positive Breast Cancer
    Tsoi, Ho
    Man, Ellen P. S.
    Chau, Ka Man
    Khoo, Ui-Soon
    CANCERS, 2021, 13 (07)
  • [27] Isolinderalactone Resistance to the Liver Injury Induced by Oxaliplatin in Rats Through Inhibiting IL-6/STAT3 Signal Pathway
    Lin, Rongwei
    Zhou, Yang
    Hu, Chao
    Yao, Hongqing
    Jin, Wangxun
    ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2023, 23 (12) : 1415 - 1420
  • [28] The glutathione peroxidase 8 (GPX8)/IL-6/STAT3 axis is essential in maintaining an aggressive breast cancer phenotype
    Khatib, Anees
    Solaimuthu, Balakrishnan
    Ben Yosef, Michal
    Abu Rmaileh, Areej
    Tanna, Mayur
    Gidi, Oren
    Frisch, Michal Schlesinger
    Axelrod, Jonathan H.
    Lichtenstein, Michal
    Shaul, Yoav D.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 117 (35) : 21420 - 21431
  • [29] tGLI1 and IL-6/IL-6R/GP130/STAT3 pathways cooperate to promote breast cancer stem cells and are co-activated in HER2-enriched and triple-negative breast cancers
    Manore, Sara G.
    Doheny, Daniel L.
    Zhu, Dongqin
    Wong, Grace L.
    Regua, Angelina T.
    Arrigo, Austin
    Wagner, Calvin J.
    Najjar, Mariana
    Lo, Hui-Wen
    CANCER RESEARCH, 2022, 82 (12)
  • [30] Discovery of novel small molecules targeting the USP21/JAK2/STAT3 axis for the treatment of triple-negative breast cancer
    Long, Lin
    Xu, Jiachi
    Qi, Xiaowen
    Pen, Yan
    Wang, Chengkun
    Jiang, Weifan
    Peng, Xue
    Hu, Zecheng
    Yi, Wenjun
    Xie, Liming
    Lei, Xiaoyong
    Wang, Zhen
    Zhuo, Linsheng
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 273