Stratification of Nontuberculous Mycobacterial Disease Risk in Type 2 Diabetes Based on Metformin Use: a Population-Based Cohort Study in South Korea

被引：0
|
作者：
Kim, Hyeon Hwa [1 ]
Kim, Seonok [2 ]
Kim, Mi Ae [3 ]
Jung, Chang Hee [4 ]
Chong, Yong Pil [5 ]
Shim, Tae Sun [1 ]
Kim, Ye-Jee [2 ]
Jo, Kyung-Wook [1 ]
机构：
[1] Univ Ulsan, Asan Med Ctr, Dept Internal Med, Coll Med,Div Pulmonol & Crit Care Med, Seoul, South Korea
[2] Univ Ulsan, Asan Med Ctr, Coll Med, Dept Clin Epidemiol & Biostat, Seoul, South Korea
[3] Keimyung Univ, Dongsan Med Ctr, Sch Med, Dept Internal Med, Daegu, South Korea
[4] Univ Ulsan, Asan Med Ctr, Dept Internal Med, Coll Med,Div Endocrinol & Metab, Seoul, South Korea
[5] Univ Ulsan, Coll Med, Asan Med Ctr, Dept Infect Dis, Seoul, South Korea
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2023年 / 67卷 / 06期
基金：
新加坡国家研究基金会;
关键词：
metformin; NTM disease; MELLITUS; TUBERCULOSIS;
D O I：
10.1128/aac.01675-22
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
In a 1:4 case-control matched analysis of data from a nationwide population-based cohort in South Korea, we evaluated whether metformin use mitigates the risk of nontuberculous mycobacterial disease in patients with type 2 diabetes. Multivariable analysis revealed no significant association of metformin use with a diminished risk for incident nontuberculous mycobacterial disease in patients with type 2 diabetes. In a 1:4 case-control matched analysis of data from a nationwide population-based cohort in South Korea, we evaluated whether metformin use mitigates the risk of nontuberculous mycobacterial disease in patients with type 2 diabetes. Multivariable analysis revealed no significant association of metformin use with a diminished risk for incident nontuberculous mycobacterial disease in patients with type 2 diabetes.
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页数：5
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