Stratification of Nontuberculous Mycobacterial Disease Risk in Type 2 Diabetes Based on Metformin Use: a Population-Based Cohort Study in South Korea

被引：0

作者：

Kim, Hyeon Hwa ^{[1
]}

Kim, Seonok ^{[2
]}

Kim, Mi Ae ^{[3
]}

Jung, Chang Hee ^{[4
]}

Chong, Yong Pil ^{[5
]}

Shim, Tae Sun ^{[1
]}

Kim, Ye-Jee ^{[2
]}

Jo, Kyung-Wook ^{[1
]}

机构：

[1] Univ Ulsan, Asan Med Ctr, Dept Internal Med, Coll Med,Div Pulmonol & Crit Care Med, Seoul, South Korea

[2] Univ Ulsan, Asan Med Ctr, Coll Med, Dept Clin Epidemiol & Biostat, Seoul, South Korea

[3] Keimyung Univ, Dongsan Med Ctr, Sch Med, Dept Internal Med, Daegu, South Korea

[4] Univ Ulsan, Asan Med Ctr, Dept Internal Med, Coll Med,Div Endocrinol & Metab, Seoul, South Korea

[5] Univ Ulsan, Coll Med, Asan Med Ctr, Dept Infect Dis, Seoul, South Korea

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2023年 / 67卷 / 06期

基金：

新加坡国家研究基金会;

关键词：

metformin; NTM disease; MELLITUS; TUBERCULOSIS;

D O I：

10.1128/aac.01675-22

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

In a 1:4 case-control matched analysis of data from a nationwide population-based cohort in South Korea, we evaluated whether metformin use mitigates the risk of nontuberculous mycobacterial disease in patients with type 2 diabetes. Multivariable analysis revealed no significant association of metformin use with a diminished risk for incident nontuberculous mycobacterial disease in patients with type 2 diabetes. In a 1:4 case-control matched analysis of data from a nationwide population-based cohort in South Korea, we evaluated whether metformin use mitigates the risk of nontuberculous mycobacterial disease in patients with type 2 diabetes. Multivariable analysis revealed no significant association of metformin use with a diminished risk for incident nontuberculous mycobacterial disease in patients with type 2 diabetes.

引用

页数：5

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