Cu2+ and pH play a key role in life systems and it is necessary to develop an effective detection method. In view of the significant advantages of the fluorescent probe, we have synthesized a dual functional fluorescent probe NCNB based on naphthalimide for detecting Cu2+ and pH. The probe NCNB is sensitive (LOD = 44.8 nM) and fast for Cu2+ (within 150 s). It can be used not only for qualitative and quantitative detection of Cu2+ in actual water samples, but also for making pH fluorescent test paper with good effect. In addition, the probe NCNB has been successfully used for imaging detection of exogenous Cu2+ in Caco-2 cells with low toxicity.
机构:
Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F UniversityShaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F University
Jia Wen
Pengyi Xia
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Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F UniversityShaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F University
Pengyi Xia
Ziming Zheng
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Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F UniversityShaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F University
Ziming Zheng
Yongqian Xu
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Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F UniversityShaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F University
Yongqian Xu
Hongjuan Li
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Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F UniversityShaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F University
Hongjuan Li
Fengyu Liu
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State Key Laboratory of Fine Chemicals, School of Chemistry, Dalian University of TechnologyShaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F University
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Ningxia Normal Univ, Coll Chem & Chem Engn, Guyuan 756000, Peoples R ChinaNingxia Normal Univ, Coll Chem & Chem Engn, Guyuan 756000, Peoples R China
Deng, Linlong
Xue, Lei
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Ningxia Normal Univ, Coll Chem & Chem Engn, Guyuan 756000, Peoples R China
Key Lab Green Catalyt Mat & Technol Ningxia Hui Au, Beijing, Peoples R ChinaNingxia Normal Univ, Coll Chem & Chem Engn, Guyuan 756000, Peoples R China
Xue, Lei
Gao, Yunke
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Ningxia Normal Univ, Coll Chem & Chem Engn, Guyuan 756000, Peoples R ChinaNingxia Normal Univ, Coll Chem & Chem Engn, Guyuan 756000, Peoples R China
Gao, Yunke
Fu, Shuai
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Ningxia Normal Univ, Coll Chem & Chem Engn, Guyuan 756000, Peoples R ChinaNingxia Normal Univ, Coll Chem & Chem Engn, Guyuan 756000, Peoples R China
Fu, Shuai
Wang, Haibin
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Ningxia Normal Univ, Coll Chem & Chem Engn, Guyuan 756000, Peoples R China
Key Lab Green Catalyt Mat & Technol Ningxia Hui Au, Beijing, Peoples R ChinaNingxia Normal Univ, Coll Chem & Chem Engn, Guyuan 756000, Peoples R China
机构:
Gansu Univ Chinese Med, Sch Clin Med 1, Lanzhou 730000, Gansu, Peoples R ChinaGansu Univ Chinese Med, Sch Clin Med 1, Lanzhou 730000, Gansu, Peoples R China
An, Yong
Li, Linyu
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Gansu Univ Chinese Med, Sch Clin Med 1, Lanzhou 730000, Gansu, Peoples R ChinaGansu Univ Chinese Med, Sch Clin Med 1, Lanzhou 730000, Gansu, Peoples R China
Li, Linyu
Li, Lepeng
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Gansu Univ Chinese Med, Sch Clin Med 1, Lanzhou 730000, Gansu, Peoples R ChinaGansu Univ Chinese Med, Sch Clin Med 1, Lanzhou 730000, Gansu, Peoples R China
Li, Lepeng
Sun, Yongqiang
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Gansu Univ Chinese Med, Sch Clin Med 1, Lanzhou 730000, Gansu, Peoples R ChinaGansu Univ Chinese Med, Sch Clin Med 1, Lanzhou 730000, Gansu, Peoples R China
Sun, Yongqiang
Li, Bo
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Gansu Univ Chinese Med, Sch Clin Med 1, Lanzhou 730000, Gansu, Peoples R China
Gansu Prov Hosp, Dept Musculoskeletal Tumor, Lanzhou 730000, Gansu, Peoples R ChinaGansu Univ Chinese Med, Sch Clin Med 1, Lanzhou 730000, Gansu, Peoples R China
Li, Bo
Wang, Peng
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China West Normal Univ, Coll Chem & Chem Engn, Chem Synth & Pollut Control Key Lab Sichuan Prov, Nanchong 637009, Peoples R ChinaGansu Univ Chinese Med, Sch Clin Med 1, Lanzhou 730000, Gansu, Peoples R China