Awareness and Acceptance of Pertussis Vaccination Among Pregnant Women in Taif Region, Saudi Arabia: A Cross-Sectional Study

Background and aim Pertussis risk increases during pregnancy when it can be passed from an infected, non-vaccinated mother to the newborn. The pertussis vaccine, Boostrix (Tdap: tetanus, diphtheria, and pertussis), was approved by the U.S. Food and Drug Administration (FDA) for immunization of pregnant women during the third trimester. The current cross-sectional study aimed to assess the awareness level of pregnant women towards pertussis. Methods The study recruited 401 pregnant women from the Taif region through an interview questionnaire, which included different questions about the socio-demographic and clinical circumstances of the participants, as well as some variable parameters, to evaluate their awareness and acceptance of the pertussis vaccination. Results The statistical analysis of the data revealed that most participants were above 30 years of age (68.1%), urban (84.5%), highly educated (57.4%), and unemployed housewives (73.1%). Medical history showed that only 15 (3.7%) of participants had the vaccine during previous pregnancies. Analysis of the data showed a significant difference of limited awareness about the disease prognosis, infection, route of transmission, and vaccination (P<0.05). This was significant among the following participants: those in the age group >30 years, without a college degree, unemployed, in the third trimester of gestation, and with a medical history of pregnancy-related diseases. Furthermore, most participants at all educational levels didn't significantly believe in the safety of the vaccine during pregnancy (P<0.05). Interestingly, most women who were without a college degree, unemployed, or not receiving a regular salary didn't intend to vaccinate their babies and neglected to obtain sufficient information about the vaccine or its side effects (P<0.05). The regression analysis revealed that women's age and education level were significant predictors of their total awareness score about the disease and its vaccination. Conclusion So, in conclusion, the study revealed that pregnant women's awareness of pertussis disease and its vaccine in the Taif region was associated with several demographic and clinical characteristics. Their acceptance of vaccination in relation to its safety or costs during pregnancy or to their infants depended significantly on their educational level and employment status. Therefore, the study recommends conducting more awareness campaigns about pertussis and its available vaccine. Also, more cross-sectional studies are required to measure the awareness of all women throughout the country.