Pre-asthma: a useful concept for prevention and disease-modification? A EUFOREA paper. Part 1-allergic asthma

被引：3

作者：

Scadding, G. K. ^{[1
,2
]}

McDonald, M. ^{[3
]}

Backer, V. ^{[4
,5
]}

Scadding, G. ^{[6
]}

Bernal-Sprekelsen, M. ^{[7
,8
]}

Conti, D. M. ^{[9
]}

De Corso, E. ^{[10
]}

Diamant, Z. ^{[11
,12
,13
,14
,15
]}

Gray, C. ^{[16
,17
,18
]}

Hopkins, C. ^{[19
]}

Jesenak, M. ^{[20
,21
,22
]}

Johansen, P. ^{[23
,24
]}

Kappen, J. ^{[25
]}

Mullol, J. ^{[26
,27
]}

Price, D. ^{[28
,29
]}

Quirce, S. ^{[30
]}

Reitsma, S. ^{[31
]}

Salmi, S. ^{[32
,33
,34
,35
]}

Senior, B. ^{[36
]}

Thyssen, J. P. ^{[37
]}

Wahn, U. ^{[38
]}

Hellings, P. W. ^{[39
,40
,41
]}

机构：

[1] Royal Natl ENT Hosp, Dept Allergy & Rhinol, London, England

[2] UCL, Div Immun & Infect, London, England

[3] Allergy Clin, Randburg, South Africa

[4] Univ Copenhagen, Dept Otorhinolaryngol Head & Neck Surg, Rigshosp, Copenhagen, Denmark

[5] Univ Copenhagen, Audiol, Rigshosp, Copenhagen, Denmark

[6] Royal Brompton Hosp, Allergy, London, England

[7] Clin Barcelona, ORL Dept, Barcelona, Spain

[8] Univ Barcelona, ORL, Barcelona, Spain

[9] European Forum Res & Educ Allergy & Airway Dis Sc, Brussels, Belgium

[10] A Gemelli Univ Hosp Fdn IRCCS, Otolaryngol Head & Neck Surg, Rome, Italy

[11] Lund Univ, Skane Univ Hosp, Inst Clin Sci, Dept Resp Med & Allergol, Lund, Sweden

[12] Charles Univ Prague, Fac Med 1, Dept Resp Med, Prague, Czech Republic

[13] Thomayer Hosp, Prague, Czech Republic

[14] Univ Groningen, Univ Med Ctr Groningen, Dept Clin Pharm & Pharmacol, Groningen, Netherlands

[15] Katholieke Univ Leuven, KU Leuven, Deptarment Microbiol Immunol & Transplantat, Leuven, Belgium

[16] Red Cross Childrens Hosp, Cape Town, South Africa

[17] Univ Cape Town, Cape Town, South Africa

[18] Kidsallergy Ctr, Cape Town, South Africa

[19] Guys & St Thomas Hosp NHS Fdn Trust, Dept Rhinol & Skull Base Surg, London, England

[20] Univ Teaching Hosp Martin, Dept Clin Immunol & Allergol, Martin, Slovakia

[21] Comenius Univ, Univ Teaching Hosp Martin, Jessenius Fac Med Martin, Dept Paediat, Martin, Slovakia

[22] Comenius Univ, Univ Teaching Hosp Martin, Jessenius Fac Med Martin, Dept Pulmonol & Phthisiol, Martin, Slovakia

[23] Univ Zurich, Dept Dermatol, Zurich, Switzerland

[24] Univ Hosp Zurich, Dept Dermatol, Zurich, Switzerland

[25] Franciscus Gasthuis & Vlietland, Dept Pulmonol, STZ Ctr Excellence Asthma COPD & Resp Allergy, Rotterdam, Netherlands

[26] Univ Barcelona, Rhinol Unit, Hosp Clin, FRCB IDIBAPS,CIBERES, Barcelona, Spain

[27] Univ Barcelona, Smell Clin, Hosp Clin, FRCB IDIBAPS,CIBERES,ENT Dept, Barcelona, Spain

[28] Observat & Pragmat Res Inst, Singapore, Singapore

[29] Univ Aberdeen, Ctr Acad Primary Care, Div Appl Hlth Sci, Aberdeen, Scotland

[30] La Paz Univ Hosp, Dept Allergy, IdiPAZ, Madrid, Spain

[31] Univ Amsterdam, Amsterdam Univ Med Ctr, Dept Otorhinolarynogol & Head Neck Surg, Locat AMC, Amsterdam, Netherlands

[32] Kuopio Univ Hosp, Dept Otorhinolaryngol, Kuopio, Finland

[33] Univ Eastern Finland, Kuopio, Finland

[34] Helsinki Univ Hosp, Dept Allergy, Inflammat Ctr, Helsinki, Finland

[35] Univ Helsinki, Helsinki, Finland

[36] Univ North Carolina Chapel Hill, Dept Otolaryngol Head & Neck Surg, Chapel Hill, NC USA

[37] Univ Copenhagen, Bispebjerg Hosp, Dept Dermatol, Copenhagen, Denmark

[38] Charite, Dept Pediat Pneumol & Immunol, Berlin, Germany

[39] Univ Hosp, Dept Otorhinolaryngol Head & Neck Surg, Leuven, Belgium

[40] Univ Hosp Leuven, Lab Allergy & Clin Immunol, Leuven, Belgium

[41] Univ Ghent, Dept Head & Skin, Upper Airways Res Lab, Ghent, Belgium

来源：

FRONTIERS IN ALLERGY | 2024年 / 4卷

关键词：

pre-asthma; asthma; quality of life; asthma natural history; predisposition; risk factors; LIFE-STYLE INTERVENTION; AIR-FLOW LIMITATION; CHILDHOOD ASTHMA; RISK-FACTORS; ALLERGIC RHINITIS; ATOPIC-DERMATITIS; BRONCHIAL HYPERRESPONSIVENESS; WEIGHT-LOSS; SCHOOL-AGE; FOLLOW-UP;

D O I：

10.3389/falgy.2023.1291185

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Asthma, which affects some 300 million people worldwide and caused 455,000 deaths in 2019, is a significant burden to suffers and to society. It is the most common chronic disease in children and represents one of the major causes for years lived with disability. Significant efforts are made by organizations such as WHO in improving the diagnosis, treatment and monitoring of asthma. However asthma prevention has been less studied. Currently there is a concept of pre- diabetes which allows a reduction in full blown diabetes if diet and exercise are undertaken. Similar predictive states are found in Alzheimer's and Parkinson's diseases. In this paper we explore the possibilities for asthma prevention, both at population level and also investigate the possibility of defining a state of pre-asthma, in which intensive treatment could reduce progression to asthma. Since asthma is a heterogeneous condition, this paper is concerned with allergic asthma. A subsequent one will deal with late onset eosinophilic asthma.

引用

页数：16

共 1 条

[1] Pre-asthma: a useful concept? A EUFOREA paper. Part 2-late onset eosinophilic asthma
Scadding, G. K.
Gray, C.
Conti, D. M.
McDonald, M.
Backer, V.
Scadding, G.
Bernal-Sprekelsen, M.
De Corso, E.
Diamant, Z.
Hopkins, C.
Jesenak, M.
Johansen, P.
Kappen, J.
Mullol, J.
Price, D.
Quirce, S.
Reitsma, S.
Toppila-Salmi, S.
Senior, B.
Thyssen, J. P.
Wahn, U.
Hellings, P. W.
FRONTIERS IN ALLERGY, 2024, 5

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