Synthesis of Indolyl Phenyl Diketones through Visible-Light-Promoted Ni-Catalyzed Intramolecular Cyclization/Oxidation Sequence of Ynones

被引：5
|
作者：
Zhou, Yufeng [1 ]
Wang, Yaping [1 ]
Xu, Peidong [1 ]
Han, Weiwei [1 ]
Xiong, Heng-Ying [1 ]
Zhang, Guangwu [1 ]
机构：
[1] Henan Univ, Coll Chem & Chem Engn, Kaifeng 475004, Peoples R China
来源：
ACS ORGANIC & INORGANIC AU | 2023年 / 4卷 / 02期
基金：
中国国家自然科学基金;
关键词：
diketones; photocatalysis; Csp(3)-Hbond functionalization; ynones; nickel; cyclization; 1,8-HYDROGEN ATOM-TRANSFER; C-BOND-CLEAVAGE; PHOTOREDOX CATALYSIS; METAL-FREE; DIARYL 1,2-DIKETONES; EFFICIENT SYNTHESIS; FACILE ACCESS; H ACTIVATION; OXIDATION; FUNCTIONALIZATION;
D O I：
10.1021/acsorginorgau.3c00060
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The combination of visible light catalysis and Ni catalysis has enabled the synthesis of indolyl phenyl diketones through the cyclization/oxidation process of ynones. This reaction proceeded under mild and base-free conditions and showed a broad scope and feasibility for gram-scale synthesis. Several natural products and biologically interesting molecules could be readily postfunctionalized by this method.
引用
收藏
页码：241 / 247
页数：7
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