The Role of Inflammation in the Pathogenesis of Psoriasis

被引：1

作者：

Costache, Raluca S. ^{[1
]}

Georgescu, Mihaela ^{[2
]}

Ghilencea, Adelina ^{[2
]}

Feroiu, Oana ^{[2
]}

Tiplica, Sorin G. ^{[3
,4
]}

Costache, Daniel O. ^{[3
,4
]}

机构：

[1] Carol Davila Univ Med & Pharm, Carol Davila Univ Cent Emergency Mil Hosp, Discipline Internal Med, Fac Med, Bucharest, Romania

[2] Carol Davila Univ Cent Emergency Mil Hosp, Dermatol Clin, Bucharest, Romania

[3] Carol Davila Univ, Carol Davila Univ Med & Pharm, Discipline Dermatol,Fac Med, Cent Emergency Mil Hosp, Bucharest, Romania

[4] Carol Davila Univ Med & Pharm, Colentina Clin Hosp, Bucharest, Romania

来源：

ROMANIAN JOURNAL OF MILITARY MEDICINE | 2023年 / 126卷 / 03期

关键词：

psoriasis vulgaris; inflammation; immune system; GENOME-WIDE ASSOCIATION; SUSCEPTIBILITY LOCI; INTERFERON-GAMMA; B-CELLS; VARIANTS; SKIN; IDENTIFICATION; MECHANISMS; GENETICS; IL-23;

D O I：

10.55453/rjmm.2023.126.3.2

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Psoriasis is a chronic inflammatory skin condition with genetic determinism characterized by the presence of well-defined, erythematous plaques, covered by white, pearly, stratified scales, located on the extension areas, the skin of the scalp, intertriginous regions. The origin of psoriasis is multifactorial, involving hereditary and environmental pathogenic mechanisms. It is triggered by various risk factors involving a variety of processes, such as inflammation, antigen presentation, cell signaling, and transcriptional regulation.

引用

页码：245 / 253

页数：9

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