Terahertz ATR sheds light on real-time exchange kinetics occurring through plasma membrane during photodynamic therapy

被引:0
|
作者
Lordon, B. [1 ]
Zheng, X. [1 ]
Mingotaud, A. -F. [2 ]
Vicendo, P. [2 ]
Brival, R. [2 ,3 ]
Fourquaux, I. [3 ]
Gibot, L. [2 ]
Gallot, G. [1 ]
机构
[1] IP Paris, Lab Opt & Biosci, Ecole polytech, INSERM,CNRS, Palaiseau, France
[2] Univ Toulouse, Lab IMRCP, CNRS UMR 5623, F-31062 Toulouse, France
[3] Univ Toulouse, Ctr Microscopie Elect Appl Biol, F-31062 Toulouse, France
关键词
D O I
10.1109/IRMMW-THz57677.2023.10299321
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
THz ATR spectroscopy provides, in a single measurement, the relative number of defects per membrane surface created by oxidative stress generated during photodynamic therapy (PDT), offering early, sensitive real-time information. THz spectroscopy is therefore a complementary technique to established (biological) assays and can be applied to any topic requiring the real-time examination of short-term plasma membrane permeabilization.
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页数:2
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