Acetyldihydropyran Semicarbazones: Two-Step Diastereoselective Synthesis from Acetylene

被引：0
|
作者：
Tatarinova, I. V. [1 ]
Lobanova, N. A. [1 ]
Ushakov, I. A. [1 ]
Schmidt, E. Yu. [1 ,2 ]
Trofimov, B. A. [1 ]
机构：
[1] Russian Acad Sci, Favorsky Irkutsk Inst Chem, Siberian Branch, Irkutsk 664033, Russia
[2] Angarsk State Tech Univ, Angarsk 665835, Russia
来源：
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2023年 / 59卷 / 03期
关键词：
acetylene; ketones; 2-acetyl-3; 4-dihydropyrans; semicarbazide hydrochloride; semicarbazones; BIOLOGICAL-ACTIVITIES;
D O I：
10.1134/S1070428023030235
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
2-Acetyl-3,4-dihydropyrans were synthesized in one step by diastereoselective reaction of acetylene with aromatic ketones, and their condensation with semicarbazide hydrochloride afforded the corresponding (E)-semicarbazones with high stereoselectivity in up to 86% yield.
引用
收藏
页码：540 / 544
页数：5
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