Analysis of Inflammatory Factors and Therapeutic Effect of Azithromycin Combined with Budesonide in Mycoplasma Pneumonia

被引:0
|
作者
Wang, Ling [1 ]
Zeng, Xiaoyan [1 ]
Chen, Biquan [1 ]
机构
[1] Anhui Prov Childrens Hosp, Dept Infect Dis, Hefei 230022, Anhui, Peoples R China
关键词
Azithromycin; budesonide; Mycoplasma pneumonia; inflammatory factors; efficacy;
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
We attempt to investigate and study the effect of azithromycin combined with budesonide treatment regimen on inflammatory factors and therapeutic effect in patients with Mycoplasma pneumonia. 100 patients with Mycoplasma pneumonia were selected in a hospital from January 2020 to December 2022 as the investigation subjects and divided them into two parts according to their admission time, control group consists of 50 patients whose treatment regimen was azithromycin orally combined with acetyl cysteine nebulization, and observation group consists of 50 patients whose treatment regimen was azithromycin orally combined with budesonide and acetyl cysteine nebulization. Detected the serum inflammatory factors and their related index values, the clinical efficacy and the occurrence of adverse reactions during the treatment period of the children with Mycoplasma pneumonia. The results showed that the serum inflammatory factor levels of the children in the observation group improved compared with those in the control group (p<0.05). Observation group possessed higher total clinical efficacy than control group (p<0.05). Observation group possessed lower incidence of adverse reactions than control group (p<0.05). The treatment regimen of azithromycin and budesonide combined with acetyl cysteine in patients with Mycoplasma pneumonia can achieve good clinical efficacy and good improvement in serum inflammatory factors, and there is no significant increase in adverse effects and high safety, which makes this treatment regimen suitable for promotion in patients with Mycoplasma pneumonia.
引用
收藏
页码:128 / 131
页数:4
相关论文
共 50 条
  • [11] Observation of the curative effect of azithromycin combined with shenmai injection in children with pneumonia and its influence on inflammatory factors
    He, Chunzhi
    Yu, Aixia
    Tian, Lin
    Dong, Shanwu
    Chen, Yongli
    BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2020, 127 : 90 - 90
  • [12] Clinical efficacy of budesonide combined with acetylcysteine in the treatment of mycoplasma pneumonia infection
    Chen, Jing
    Zhu, Ying
    Zheng, Chunfeng
    Zhao, Wei
    Liu, Qi
    IMMUNITY INFLAMMATION AND DISEASE, 2023, 11 (11)
  • [13] Effects of a combination of erythromycin sequential therapy and azithromycin on lung function and inflammatory factors in children with severe mycoplasma pneumonia
    Wang, Fang
    Nan, Kai
    Hao, Lingfeng
    Li, Haitao
    Wang, Congmin
    Zhang, Lina
    Jiang, Lili
    Tian, Yunxiao
    PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2021, 34 (06) : 2447 - 2454
  • [14] RETRACTED: The Effect of Azithromycin Combined with Palm Massage on Pulmonary Function of Children with Mycoplasma Pneumonia (Retracted Article)
    Li, Haiyan
    Xu, Dandan
    EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2022, 2022
  • [15] RETRACTED: Efficacy of Jiedu Pingsou Decoction Combined with Azithromycin in the Treatment of Children with Mycoplasma Pneumonia and Its Effects on Inflammatory Factors and Immune Function (Retracted Article)
    Lin, Shaoli
    Wang, Shiyun
    Zhang, Juan
    Zhuang, Min
    Meng, Zhen
    Liu, Jianhua
    JOURNAL OF HEALTHCARE ENGINEERING, 2022, 2022
  • [16] Clinical observation of Tanreqing combined with azithromycin in sequential treatment of mycoplasma pneumonia in children
    Han, Jia
    Cao, Lian
    Liang, Yanhui
    Wang, Yuxia
    MINERVA PEDIATRICS, 2023, 75 (01): : 161 - 163
  • [17] Effect of bronchofiberscopic lavage with budesonide suspension on refractory mycoplasma pneumoniae pneumonia
    Li, Ya
    Yang, Wei
    Wu, Xin
    Gou, Xiaohua
    PAKISTAN JOURNAL OF MEDICAL SCIENCES, 2022, 38 (04) : 922 - 927
  • [18] Effect of electronic fibrobronchoscope alveolar lavage combined with local administration of budesonide on the efficacy of Mycoplasma pneumoniae pneumonia in children
    Xu, Fengqin
    Zhang, Qi
    Chen, Fuzhe
    ALLERGOLOGIA ET IMMUNOPATHOLOGIA, 2024, 52 (06) : 51 - 57
  • [19] Clinical effect of sequential therapy with azithromycin in children mycoplasma pneumoniae pneumonia
    Wang, Jianlong
    Yang, Cun
    PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2018, 31 (04) : 1649 - 1652
  • [20] Clinical significance of serum microRNA-146a and inflammatory factors in children with Mycoplasma pneumoniae pneumonia after azithromycin treatment
    Wang, Zhe
    Chu, Chu
    Ding, Ying
    Li, Yuqin
    Lu, Chunyu
    JORNAL DE PEDIATRIA, 2024, 100 (01) : 108 - 115