Diagnostic accuracy of real- time shear wave elastography in the evaluation of prostatic lesion

This research aims to compare the diagnostic accuracy of ultrasound elastography to histology in evaluating prostate masses and assess its ability to distinguish malignant from benign diseases. The research involved 60 individuals with elevated PSA values (> 4 ng/ml) and aberrant DRE results were sent to our department. The trial lasted from August 2020 until February 2022. All patients gave informed consent and were aware of the potential complications of the biopsy. All the patients had B mode. Transrectal Ultrasonography, colour Doppler imaging, and transrectal real-time strain elastography were performed. The final diagnosis was confirmed with histopathological examination. The institutional ethics committee approved the study, and all patients obtained informed consent. In our study, the strain ratio has a sensitivity of 81.4%, a specificity of 83%, a positive predictive value of 88.4%, a negative predictive value of 83.5%, and an accuracy of 91.5% when a cut-off point of 5 is used to differentiate benign from malignant lesions. According to our results, prostate Ultrasonography coupled with elastography could be a valuable method for diagnosing malignant lesions and helps in targeting biopsy.