Severe ulcerative colitis induced by COVID-19 vaccination

被引：1

作者：

Taida, Takashi ^{[1
,2
]}

Kato, Jun ^{[1
,2
]}

Ishikawa, Kentaro ^{[3
]}

Akizue, Naoki ^{[1
]}

Ohta, Yuki ^{[1
,2
]}

Okimoto, Kenichiro ^{[1
]}

Saito, Keiko ^{[1
]}

Matsusaka, Keisuke ^{[4
]}

Matsumura, Tomoaki ^{[1
]}

Kato, Naoya ^{[1
]}

机构：

[1] Chiba Univ, Grad Sch Med, Dept Gastroenterol, Chiba, Japan

[2] Chiba Univ Hosp, Endoscop Ctr, Chiba, Japan

[3] Chiba Rosai Hosp, Dept Gastroenterol, Chiba, Japan

[4] Chiba Univ Hosp, Dept Pathol, Chiba, Japan

来源：

CLINICAL JOURNAL OF GASTROENTEROLOGY | 2024年 / 17卷 / 03期

关键词：

COVID-19; Vaccine; Inflammatory bowel disease;

D O I：

10.1007/s12328-024-01926-x

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

A 37-year-old woman developed severe colitis with diffuse mucosal erythema and ulcerations throughout the entire colon after the 3rd vaccination of COVID-19. Stool culture was negative, and the pathological findings showed increased lymphoplasmacytic and neutrophilic infiltration in the colonic lamina propria, which were consistent with ulcerative colitis. After the treatment with anti-tumor necrosis factor-alpha agent, the ulceration markedly improved with development of severe colonic stenosis, which was successfully dilated with endoscopic balloon dilation. In case of COVID-19 vaccination, it should be noted that vaccination could be a trigger for the onset of UC.

引用

页码：447 / 450

页数：4

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