A NEW APPROACH TO MODEL INTESTINAL FIBROSIS IN CROHN'S DISEASE PATIENTS USING MESENCHYMAL CELLS GENERATED FROM IPSC-DERIVED HUMAN INTESTINAL ORGANOIDS

被引:0
|
作者
Bay, Olivia K.
Patel, Shachi
Valencia, Christian E. Wong
Casero, David
Targan, Stephan
Barrett, Robert J.
机构
关键词
D O I
暂无
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Tu1241
引用
收藏
页码:S1005 / S1005
页数:1
相关论文
共 50 条
  • [31] Application of Human Induced Pluripotent Stem Cell-Derived Intestinal Organoids as a Model of Epithelial Damage and Fibrosis in Inflammatory Bowel Disease
    Onozato, Daichi
    Akagawa, Takumi
    Kida, Yuriko
    Ogawa, Isamu
    Hashita, Tadahiro
    Iwao, Takahiro
    Matsunaga, Tamihide
    BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2020, 43 (07) : 1088 - 1095
  • [32] Intestinal fibrosis in Crohn's disease patients is marked by up-regulation of innate immune cells and mucosal B cells
    Creyns, B.
    Gabriele, D.
    Jonathan, C.
    Verstockt, B.
    Bislenghi, G.
    Marc, F.
    Vermeire, S.
    Van Assche, G.
    Ceuppens, J.
    D'Hoore, A.
    De Hertogh, G.
    Breynaert, C.
    JOURNAL OF CROHNS & COLITIS, 2020, 14 : S122 - S123
  • [33] Early Signs of Molecular Defects in iPSC-Derived Neural Stems Cells from Patients with Familial Parkinson's Disease
    Akrioti, Elissavet
    Karamitros, Timokratis
    Gkaravelas, Panagiotis
    Kouroupi, Georgia
    Matsas, Rebecca
    Taoufik, Era
    BIOMOLECULES, 2022, 12 (07)
  • [34] Deep learning model to differentiate Crohn's disease from intestinal tuberculosis using histopathological whole slide images from intestinal specimens
    Liu, Xinning
    Li, Fei
    Xu, Jie
    Ma, Jinting
    Duan, Xiaoyu
    Mao, Ren
    Chen, Minhu
    Chen, Zhihui
    Huang, Yan
    Jiang, Jingyi
    Huang, Bingsheng
    Ye, Ziyin
    VIRCHOWS ARCHIV, 2024, 484 (06) : 965 - 976
  • [35] Failure of receptor expression and IL-10 binding by intestinal epithelial cells derived from patients with active Crohn's disease
    Zhao, LM
    Burakoff, R
    Mayer, L
    Panja, A
    GASTROENTEROLOGY, 1999, 116 (04) : A851 - A851
  • [36] ALTERNATION OF INTESTINAL EPITHELIAL STEM CELLS COMPARTMENT IN RESPONSE TO INFLAMMATION FROM PATIENTS WITH CROHN'S DISEASE
    Feng, Rui
    Yang, Hong-sheng
    Zhang, Sheng-Hong
    Xu, Shu
    Qiu, Yun
    Feng, Ting
    Chen, Minhu
    GASTROENTEROLOGY, 2018, 154 (06) : S271 - S271
  • [37] Constitutive STAT3 activation in intestinal T cells from patients with Crohn's disease
    Lovato, P
    Brender, C
    Agnholt, J
    Kelsen, J
    Kaltoft, K
    Svejgaard, A
    Eriksen, KW
    Woetmann, A
    Odum, N
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (19) : 16777 - 16781
  • [38] Intestinal dendritic cells from patients with Crohn's disease are up-regulated for inflammatory responses
    Smythies, LE
    Ochsenbauer-Jambor, C
    Mosteller-Bamum, M
    Smith, PD
    GASTROENTEROLOGY, 2005, 128 (04) : A87 - A87
  • [39] The change of the electrophysiological parameters using human intestinal tissues from ulcerative colitis and Crohn's disease
    Nakai, Daisuke
    Miyake, Masateru
    JOURNAL OF PHARMACOLOGICAL SCIENCES, 2022, 150 (02) : 90 - 93
  • [40] Human intestinal smooth muscle (hism) cells from Crohn's disease patients display altered cytosolic calcium mobilization.
    Komas, N
    Gosselin, C
    Willey, A
    Graham, M
    O'Connor-McCourt, M
    Hollenberg, M
    Schwartz, JL
    MOLECULAR BIOLOGY OF THE CELL, 1998, 9 : 250A - 250A